Title |
The Changing Face of Head and Neck Cancer in the 21st Century: The Impact of HPV on the Epidemiology and Pathology of Oral Cancer
|
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Published in |
Head and Neck Pathology, February 2009
|
DOI | 10.1007/s12105-009-0100-y |
Pubmed ID | |
Authors |
William H. Westra |
Abstract |
The longstanding notion that head and neck squamous cell carcinoma (HNSCC) is a uniform disease process is changing. Divergence in epidemiologic trends among HNSCCs arising in different anatomic subsites has introduced a view that HNSCC is a heterogeneous group. Analysis of molecular genetic changes discloses not just individual tumor differences, but also consistent large-scale differences that permit the recognition of important tumor subtypes. One recently recognized subtype is the human papillomavirus (HPV)-positive oropharyngeal carcinoma. HPV-positive oropharyngeal cancer now dominates the head and neck oncology landscape, and its escalating incidence is impacting on diagnostic, preventive and therapeutic practices. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Spain | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Scientists | 1 | 50% |
Members of the public | 1 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Spain | 2 | 1% |
Portugal | 1 | <1% |
Tanzania, United Republic of | 1 | <1% |
Germany | 1 | <1% |
Mexico | 1 | <1% |
United States | 1 | <1% |
Unknown | 188 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 34 | 17% |
Student > Postgraduate | 23 | 12% |
Researcher | 22 | 11% |
Student > Ph. D. Student | 22 | 11% |
Student > Bachelor | 17 | 9% |
Other | 44 | 23% |
Unknown | 33 | 17% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 96 | 49% |
Biochemistry, Genetics and Molecular Biology | 21 | 11% |
Agricultural and Biological Sciences | 18 | 9% |
Nursing and Health Professions | 5 | 3% |
Engineering | 3 | 2% |
Other | 10 | 5% |
Unknown | 42 | 22% |