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Golf: an Olfactory Neuron Specific-G Protein Involved in Odorant Signal Transduction

Overview of attention for article published in Science, May 1989
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (98th percentile)
  • High Attention Score compared to outputs of the same age and source (91st percentile)

Mentioned by

news
2 news outlets
patent
13 patents
wikipedia
3 Wikipedia pages

Citations

dimensions_citation
781 Dimensions

Readers on

mendeley
165 Mendeley
citeulike
1 CiteULike
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Title
Golf: an Olfactory Neuron Specific-G Protein Involved in Odorant Signal Transduction
Published in
Science, May 1989
DOI 10.1126/science.2499043
Pubmed ID
Authors

David T. Jones, Randall R. Reed

Abstract

Biochemical and electrophysiological studies suggest that odorants induce responses in olfactory sensory neurons via an adenylate cyclase cascade mediated by a G protein. An olfactory-specific guanosine triphosphate (GTP)-binding protein alpha subunit has now been characterized and evidence is presented suggesting that this G protein, termed Golf, mediates olfaction. Messenger RNA that encodes Golf alpha is expressed in olfactory neuroephithelium but not in six other tissues tested. Moreover, within the olfactory epithelium, Golf alpha appears to be expressed only by the sensory neurons. Specific antisera were used to localize Golf alpha protein to the sensory apparatus of the receptor neurons. Golf alpha shares extensive amino acid identity (88 percent) with the stimulatory G protein, Gs alpha. The expression of Golf alpha in S49 cyc- kin- cells, a line deficient in endogenous stimulatory G proteins, demonstrates its capacity to stimulate adenylate cyclase in a heterologous system.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 165 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 3 2%
Germany 2 1%
United Kingdom 1 <1%
Denmark 1 <1%
Canada 1 <1%
Unknown 157 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 42 25%
Student > Bachelor 23 14%
Student > Master 18 11%
Researcher 17 10%
Professor 11 7%
Other 27 16%
Unknown 27 16%
Readers by discipline Count As %
Agricultural and Biological Sciences 64 39%
Biochemistry, Genetics and Molecular Biology 22 13%
Neuroscience 17 10%
Medicine and Dentistry 12 7%
Chemistry 5 3%
Other 10 6%
Unknown 35 21%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 23. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 March 2023.
All research outputs
#1,434,004
of 23,504,445 outputs
Outputs from Science
#22,584
of 78,600 outputs
Outputs of similar age
#166
of 15,011 outputs
Outputs of similar age from Science
#12
of 149 outputs
Altmetric has tracked 23,504,445 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 93rd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 78,600 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 63.3. This one has gotten more attention than average, scoring higher than 71% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 15,011 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 98% of its contemporaries.
We're also able to compare this research output to 149 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 91% of its contemporaries.