| Title |
Behavioral genomics of honeybee foraging and nest defense
|
|---|---|
| Published in |
The Science of Nature, December 2006
|
| DOI | 10.1007/s00114-006-0183-1 |
| Pubmed ID | |
| Authors |
Greg J. Hunt, Gro V. Amdam, David Schlipalius, Christine Emore, Nagesh Sardesai, Christie E. Williams, Olav Rueppell, Ernesto Guzmán-Novoa, Miguel Arechavaleta-Velasco, Sathees Chandra, M. Kim Fondrk, Martin Beye, Robert E. Page |
| Abstract |
The honeybee has been the most important insect species for study of social behavior. The recently released draft genomic sequence for the bee will accelerate honeybee behavioral genetics. Although we lack sufficient tools to manipulate this genome easily, quantitative trait loci (QTLs) that influence natural variation in behavior have been identified and tested for their effects on correlated behavioral traits. We review what is known about the genetics and physiology of two behavioral traits in honeybees, foraging specialization (pollen versus nectar), and defensive behavior, and present evidence that map-based cloning of genes is more feasible in the bee than in other metazoans. We also present bioinformatic analyses of candidate genes within QTL confidence intervals (CIs). The high recombination rate of the bee made it possible to narrow the search to regions containing only 17-61 predicted peptides for each QTL, although CIs covered large genetic distances. Knowledge of correlated behavioral traits, comparative bioinformatics, and expression assays facilitated evaluation of candidate genes. An overrepresentation of genes involved in ovarian development and insulin-like signaling components within pollen foraging QTL regions suggests that an ancestral reproductive gene network was co-opted during the evolution of foraging specialization. The major QTL influencing defensive/aggressive behavior contains orthologs of genes involved in central nervous system activity and neurogenesis. Candidates at the other two defensive-behavior QTLs include modulators of sensory signaling (Am5HT(7) serotonin receptor, AmArr4 arrestin, and GABA-B-R1 receptor). These studies are the first step in linking natural variation in honeybee social behavior to the identification of underlying genes. |
Mendeley readers
The data shown below were compiled from readership statistics for 263 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 7 | 3% |
| Germany | 2 | <1% |
| Brazil | 2 | <1% |
| Indonesia | 1 | <1% |
| Netherlands | 1 | <1% |
| Portugal | 1 | <1% |
| New Zealand | 1 | <1% |
| Finland | 1 | <1% |
| Benin | 1 | <1% |
| Other | 1 | <1% |
| Unknown | 245 | 93% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 60 | 23% |
| Student > Ph. D. Student | 55 | 21% |
| Student > Master | 28 | 11% |
| Student > Bachelor | 26 | 10% |
| Professor > Associate Professor | 19 | 7% |
| Other | 44 | 17% |
| Unknown | 31 | 12% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 178 | 68% |
| Biochemistry, Genetics and Molecular Biology | 21 | 8% |
| Neuroscience | 10 | 4% |
| Environmental Science | 8 | 3% |
| Physics and Astronomy | 2 | <1% |
| Other | 7 | 3% |
| Unknown | 37 | 14% |
Attention Score in Context
This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 February 2024.
All research outputs
#4,965,094
of 23,794,258 outputs
Outputs from The Science of Nature
#569
of 2,195 outputs
Outputs of similar age
#21,666
of 160,014 outputs
Outputs of similar age from The Science of Nature
#13
of 28 outputs
Altmetric has tracked 23,794,258 research outputs across all sources so far. Compared to these this one has done well and is in the 76th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,195 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 13.5. This one has gotten more attention than average, scoring higher than 72% of its peers.
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We're also able to compare this research output to 28 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 53% of its contemporaries.