Title |
Effects of central 5-hydroxytryptamine depletion on sensitivity to delayed and probabilistic reinforcement
|
---|---|
Published in |
Psychopharmacology, November 2000
|
DOI | 10.1007/s002130000542 |
Pubmed ID | |
Authors |
S. Mobini, T.-J. Chiang, M.-Y. Ho, C.M. Bradshaw, E. Szabadi |
Abstract |
The ascending 5-hydroxytryptaminergic (5-HTergic) pathways are believed to be involved in "impulse control". Rats whose 5-HTergic pathways have been destroyed are more liable than intact rats to select a smaller, immediate reinforcer rather than a larger, delayed reinforcer (impulsive choice), and recent evidence indicates that this effect of central 5-HT depletion reflects a change in the rate of time discounting (i.e. a change in the rate at which reinforcers become devalued as a function of delay). Delay of reinforcement and uncertainty of reinforcer delivery are believed to have equivalent effects on choice behaviour. However, it is not known whether central 5-HT depletion affects choice between probabilistic reinforcers. |
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Switzerland | 1 | <1% |
Portugal | 1 | <1% |
South Africa | 1 | <1% |
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Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 31 | 23% |
Student > Ph. D. Student | 30 | 22% |
Student > Master | 15 | 11% |
Professor > Associate Professor | 13 | 10% |
Student > Bachelor | 8 | 6% |
Other | 19 | 14% |
Unknown | 18 | 13% |
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Economics, Econometrics and Finance | 4 | 3% |
Other | 12 | 9% |
Unknown | 26 | 19% |