You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output.
Click here to find out more.
Mendeley readers
Attention Score in Context
| Title |
Ancient Missense Mutations in a New Member of the RoRet Gene Family Are Likely to Cause Familial Mediterranean Fever
|
|---|---|
| Published in |
Cell, August 1997
|
| DOI | 10.1016/s0092-8674(00)80539-5 |
| Pubmed ID | |
| Authors |
The International FMF Consortium |
| Abstract |
Familial Mediterranean fever (FMF) is a recessively inherited disorder characterized by dramatic episodes of fever and serosal inflammation. This report describes the cloning of the gene likely to cause FMF from a 115-kb candidate interval on chromosome 16p. Three different missense mutations were identified in affected individuals, but not in normals. Haplotype and mutational analyses disclosed ancestral relationships among carrier chromosomes in populations that have been separated for centuries. The novel gene encodes a 3.7-kb transcript that is almost exclusively expressed in granulocytes. The predicted protein, pyrin, is a member of a family of nuclear factors homologous to the Ro52 autoantigen. The cloning of the FMF gene promises to shed light on the regulation of acute inflammatory responses. |
Mendeley readers
The data shown below were compiled from readership statistics for 263 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Australia | 2 | <1% |
| Turkey | 1 | <1% |
| Germany | 1 | <1% |
| United Kingdom | 1 | <1% |
| United States | 1 | <1% |
| Unknown | 257 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 45 | 17% |
| Student > Ph. D. Student | 34 | 13% |
| Student > Master | 29 | 11% |
| Student > Doctoral Student | 19 | 7% |
| Student > Bachelor | 19 | 7% |
| Other | 63 | 24% |
| Unknown | 54 | 21% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 78 | 30% |
| Biochemistry, Genetics and Molecular Biology | 47 | 18% |
| Agricultural and Biological Sciences | 37 | 14% |
| Immunology and Microbiology | 16 | 6% |
| Nursing and Health Professions | 4 | 2% |
| Other | 15 | 6% |
| Unknown | 66 | 25% |
Attention Score in Context
This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 October 2020.
All research outputs
#5,452,627
of 25,394,764 outputs
Outputs from Cell
#9,816
of 17,169 outputs
Outputs of similar age
#4,284
of 28,138 outputs
Outputs of similar age from Cell
#54
of 97 outputs
Altmetric has tracked 25,394,764 research outputs across all sources so far. Compared to these this one has done well and is in the 75th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 17,169 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 59.2. This one is in the 33rd percentile – i.e., 33% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 28,138 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.
We're also able to compare this research output to 97 others from the same source and published within six weeks on either side of this one. This one is in the 35th percentile – i.e., 35% of its contemporaries scored the same or lower than it.