| Title |
Cathinone, an alkaloid from khat leaves with an amphetamine-like releasing effect
|
|---|---|
| Published in |
Psychopharmacology, July 1981
|
| DOI | 10.1007/bf00427108 |
| Pubmed ID | |
| Authors |
Peter Kalix |
| Abstract |
Khat leaves, widely used as a stimulant in East Africa and the Arab Peninsula, contain the alkaloid (--)-cathinone. The effects of this substance on the efflux of radioactivity from rabbit striatal slices prelabelled with 3H-dopamine were examined. It was found that low concentrations of (--)cathinone enhance the release of radioactivity in a dose-dependent manner, and that (--)cathinone was capable of sustaining the enhanced release induced by (+)amphetamine. Pretreatment of the tissue with cocaine, which is known to prevent the induction of release by (+)amphetamine, inhibited the efflux increase caused by (--)-cathinone. These observations suggest that amphetamine and the active principle of khat leaves have an analogous mechanism of action. |
Mendeley readers
The data shown below were compiled from readership statistics for 14 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 7% |
| Spain | 1 | 7% |
| Unknown | 12 | 86% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 5 | 36% |
| Student > Ph. D. Student | 3 | 21% |
| Lecturer | 1 | 7% |
| Student > Bachelor | 1 | 7% |
| Researcher | 1 | 7% |
| Other | 1 | 7% |
| Unknown | 2 | 14% |
| Readers by discipline | Count | As % |
|---|---|---|
| Chemistry | 6 | 43% |
| Pharmacology, Toxicology and Pharmaceutical Science | 1 | 7% |
| Psychology | 1 | 7% |
| Biochemistry, Genetics and Molecular Biology | 1 | 7% |
| Medicine and Dentistry | 1 | 7% |
| Other | 1 | 7% |
| Unknown | 3 | 21% |
Attention Score in Context
This research output has an Altmetric Attention Score of 18. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 April 2022.
All research outputs
#1,975,018
of 25,391,066 outputs
Outputs from Psychopharmacology
#467
of 5,409 outputs
Outputs of similar age
#151
of 6,903 outputs
Outputs of similar age from Psychopharmacology
#1
of 8 outputs
Altmetric has tracked 25,391,066 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 92nd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 5,409 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.9. This one has done particularly well, scoring higher than 90% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 6,903 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 97% of its contemporaries.
We're also able to compare this research output to 8 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them