Title |
Managing Malignant Cerebral Infarction
|
---|---|
Published in |
Current Treatment Options in Neurology, December 2010
|
DOI | 10.1007/s11940-010-0110-9 |
Pubmed ID | |
Authors |
J. Marc Simard, Juan Sahuquillo, Kevin N. Sheth, Kristopher T. Kahle, Brian P. Walcott |
Abstract |
Managing patients with malignant cerebral infarction remains one of the foremost challenges in medicine. These patients are at high risk for progressive neurologic deterioration and death due to malignant cerebral edema, and they are best cared for in the intensive care unit of a comprehensive stroke center. Careful initial assessment of neurologic function and of findings on MRI, coupled with frequent reassessment of clinical and radiologic findings using CT or MRI are mandatory to promote the prompt initiation of treatments that will ensure the best outcome in these patients. Significant deterioration in either neurologic function or radiologic findings or both demand timely treatment using the best medical management, which may include osmotherapy (mannitol or hypertonic saline), endotracheal intubation, and mechanical ventilation. Under appropriate circumstances, decompressive craniectomy may be warranted to improve outcome or to prevent death. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 3 | 3% |
Brazil | 2 | 2% |
Unknown | 84 | 94% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 11 | 12% |
Researcher | 10 | 11% |
Student > Postgraduate | 10 | 11% |
Student > Doctoral Student | 10 | 11% |
Student > Master | 10 | 11% |
Other | 23 | 26% |
Unknown | 15 | 17% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 48 | 54% |
Neuroscience | 9 | 10% |
Biochemistry, Genetics and Molecular Biology | 4 | 4% |
Nursing and Health Professions | 2 | 2% |
Agricultural and Biological Sciences | 2 | 2% |
Other | 3 | 3% |
Unknown | 21 | 24% |