| Title |
Sensitivity of Erythrocyte Sedimentation Rate and C‐reactive Protein in Childhood Bone and Joint Infections
|
|---|---|
| Published in |
Clinical Orthopaedics & Related Research, June 2009
|
| DOI | 10.1007/s11999-009-0936-1 |
| Pubmed ID | |
| Authors |
Markus Pääkkönen, Markku J. T. Kallio, Pentti E. Kallio, Heikki Peltola |
| Abstract |
In addition to the examination of clinical signs, several laboratory markers have been measured for diagnostics and monitoring of pediatric septic bone and joint infections. Traditionally erythrocyte sedimentation rate (ESR) and leukocyte cell count have been used, whereas C-reactive protein (CRP) has gained in popularity. We monitored 265 children at ages 3 months to 15 years with culture-positive osteoarticular infections with a predetermined series of ESR, CRP, and leukocyte count measurements. On admission, ESR exceeded 20 mm/hour in 94% and CRP exceeded 20 mg/L in 95% of the cases, the mean (+/- standard error of the mean) being 51 +/- 2 mm/hour and 87 +/- 4 mg/L, respectively. ESR normalized in 24 days and CRP in 10 days. Elevated CRP gave a slightly better sensitivity in diagnostics than ESR, but best sensitivity was gained with the combined use of ESR and CRP (98%). Elevated ESR or CRP was seen in all cases during the first 3 days. Measuring ESR and CRP on admission can help the clinician rule out an acute osteoarticular infection. CRP normalizes faster than ESR, providing a clear advantage in monitoring recovery. |
Mendeley readers
The data shown below were compiled from readership statistics for 175 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | <1% |
| Ukraine | 1 | <1% |
| Singapore | 1 | <1% |
| Brazil | 1 | <1% |
| Unknown | 171 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Postgraduate | 25 | 14% |
| Other | 21 | 12% |
| Student > Doctoral Student | 18 | 10% |
| Researcher | 14 | 8% |
| Student > Bachelor | 12 | 7% |
| Other | 39 | 22% |
| Unknown | 46 | 26% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 104 | 59% |
| Agricultural and Biological Sciences | 5 | 3% |
| Nursing and Health Professions | 5 | 3% |
| Business, Management and Accounting | 2 | 1% |
| Immunology and Microbiology | 2 | 1% |
| Other | 9 | 5% |
| Unknown | 48 | 27% |
Attention Score in Context
This research output has an Altmetric Attention Score of 15. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 January 2021.
All research outputs
#2,550,198
of 25,998,826 outputs
Outputs from Clinical Orthopaedics & Related Research
#392
of 7,430 outputs
Outputs of similar age
#9,039
of 127,639 outputs
Outputs of similar age from Clinical Orthopaedics & Related Research
#6
of 42 outputs
Altmetric has tracked 25,998,826 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 90th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 7,430 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.8. This one has done particularly well, scoring higher than 94% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 127,639 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 93% of its contemporaries.
We're also able to compare this research output to 42 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 85% of its contemporaries.