Peptides: The Wave of the Future

Table of Contents

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   Book Overview
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   Chapter 2 Genomics: From Microbes to Man
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   Chapter 3 Fluorous Methods for Synthesis and Separation of Organic Molecules: From Separating Mixtures to Making Mixtures
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   Chapter 4 Synthesis of β and γ-Substituted Prolines for Conformation-Activity Relationship Studies of the α-MSH Analogue MT-II
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   Chapter 5 The General Asymmetric Synthesis of Syn - and Anti -β-substituted Cysteine and Serine Derivatives
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   Chapter 7 An Efficient Method for Large-Scale Synthesis of Stereochemically Defined and Conformationally Constrained β-Substituted or α,β-Disubstituted Amino Acids
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   Chapter 8 Synthesis of Amino Acids with Novel Biophysical Properties
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   Chapter 9 Two Novel and Efficient Approaches to Synthesis of Enantiopure Dipeptide β-Turn Mimetics: Indolizidinone Amino Acids
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   Chapter 11 Ethyl Nitroacetate as a Useful Synthon for the Synthesis of Orthogonally Protected, Poly-Functional C αα -Disubstituted Amino Acids
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    Chapter 12 Synthesis of β-Benzo[ b ]thiophene Dehydroamino Acids by Suzuki Palladium Catalyzed Cross Coupling
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    Chapter 14 One-Pot Conversion of Azides to Protected Guanidines via the Staudinger Reduction; Synthesis and Utilization of the Phe-Arg Hydroxyethylene Dipeptide Isostere
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    Chapter 17 Facile Synthesis of a Constrained Dipeptide Unit (DPU) for Use as a β-Sheet Promoter
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    Chapter 18 Synthesis of N α -(Fluoren-9-ylmethoxycarbonyl)- N ε -[(7- methoxycoumarin-4-yl)-acetyl]-L-lysine for Use in Solid-Phase Synthesis of Fluorogenic Substrates
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    Chapter 19 Preparation of β-Amino-α-mercapto Acids and Amides: Stereocontrolled Syntheses of 2′-Sulfur Analogues of the Taxol C-13 Side Chain, Both syn and and S -Acetyl- N -benzoyl-3-phenylisocysteine
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    Chapter 20 New Approach for Preparation of C-Glycoamino Acid Building Blocks
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    Chapter 21 New Quencher Derivatives for Fluorescence Quenching Peptide Assays
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    Chapter 22 Preparation of (2 S )-2-Amino-3-(2-(2,2,5,7,8-pentamethylchroman-6-sulfonyl)-1 H -indol-3-yl)-propionic acid and Its Incorporation into Antibacterial Lactoferricin Peptides
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    Chapter 23 UniChemo Protection (UCP)
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    Chapter 24 An Improved Synthesis of Fmoc-Asp(O-3-methylpent-3-yl)-OH, an Aspartate Derivative That Resists Base Induced Aspartimide Formation
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    Chapter 25 Systematic Investigation of the Aspartimide Problem
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    Chapter 26 Ninhydrin as a Reversible Protecting Group of N-Terminal Cysteine
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    Chapter 28 N in -4-Nitrobenzenesulfonyl Tryptophan: A Convenient Preparation of N α -Boc and N α -Fmoc Derivatives
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    Chapter 29 Syntheses of Difficult Hydrophobic Sequences Using 2-(4-Nitrophenyl)sulfonylethoxycarbonyl(Nsc)- N α -(2-hydroxy- 4-methoxybenzyl)Ala-OH: (Ala) 10 -Valine, (Ala) 15 -Valine
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    Chapter 30 A Highly Efficient Method for Synthesis of Fmoc-Lysine(Mmt)-OH
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    Chapter 31 A New Practical Approach to the Synthesis of Fmoc-L-Cysteine
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    Chapter 32 A Novel Protocol of Solid Phase Peptide Synthesis with 2-(4-Nitrophenyl)sulfonylethoxycarbonyl(Nsc)-Amino Acids
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    Chapter 33 S -Xanthenyl Protected 1-Thiosugars as Building Blocks for Glycopeptide Assembly
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    Chapter 34 Late Deprotection Difficulties During SPPS Depend on the Preceding Sequence
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    Chapter 35 Towards a Selective Boc Deprotection on Acid Cleavable Resin
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    Chapter 37 Acidic Cleavage of the Side Chain Protecting Groups of Peptides Attached to a Modified Polystyrene Carrier: Synthesis of Peptide Generics
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    Chapter 38 The Use of a Novel Safety Catch Linker for BOC-Based Assembly of Cyclic Peptide Libraries
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    Chapter 39 Diurethanyl 1 H -Benzotriazole-1-carboxamidines as Guanidinylating Reagents
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    Chapter 41 Synthesis of the Two Isomeric Benzo Derivatives of 1-Hydroxy-7-azabenzotriazole and Preliminary Studies of Their Effectiveness as Coupling Reagents
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    Chapter 42 Optimization of Coupling Methods for the Introduction of Mono-Benzyl Phosphate Esters of Fmoc Protected Phosphoamino Acids
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    Chapter 43 HATU-HOAt-CuCl 2 : A Reliable Racemization-Free Segment Coupling System
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    Chapter 44 Search for a Safe, Inexpensive and Convenient Amidation Process for Protected Amino Acids and/or Peptides
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    Chapter 45 Extending Synthetic Access to Proteins
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    Chapter 46 A New Scaffold for Amide Ligation
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    Chapter 48 Synthesis of Oligodeoxynucleotide-Peptide Conjugates Using Hydrazone Chemical Ligation
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    Chapter 50 Synthesis of N to C Terminal Cyclic Analogues of α-Conotoxin Iml by Chemoselective Ligation of Unprotected Linear Precursors
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    Chapter 51 Total Chemical Synthesis of κ-Casein Using Native Ligation Methodology
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    Chapter 52 Fmoc Chemistry Compatible Methods for Thio-Ligation Assembly of Proteins
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    Chapter 53 Simultaneous Lipidation of a Multi-Epitope Peptide Cocktail by Chemoselective Hydrazone Formation
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    Chapter 54 Privilege Structures: New Strategies for the Synthesis of Cyclic Tetrapeptides
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    Chapter 55 Incorporation of a cis-Amide Bond Isostere in the Synthesis of Cyclic Tetrapeptides
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    Chapter 56 Covalent Control of Shape and Folding in Peptides by Ring-Closing Metathesis
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    Chapter 59 An Efficient Synthesis of Integrin Antagonists cyclo (-RGDfK-), cyclo(-GRGDfK-) and Their Conjugates with MAG3 Chelate
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    Chapter 63 Vinyl Sulfide Cyclized Analogues of Angiotensin II with High Affinity to the AT 1 -Receptor
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    Chapter 64 Strategies for the Synthesis of Novel Head-to-Side Chain Cyclic Peptides: Application to Dynorphin A Analogs
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    Chapter 65 Study on the Influence of Different Metal Ions on Cyclization of Linear Pentapeptides and Heptapeptide
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    Chapter 66 Disulfide Bond Formation of a Hydrophobic Peptide by Dimethyl Sulfoxide
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    Chapter 67 Stereoselective Synthesis of Transition State Analog Inhibitors of DPP-IV Using 2-Substituted Thiazoles
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    Chapter 69 An Efficient Approach for the Synthesis of Salmon Calcitonin Using Oxazolidine Dipeptides
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    Chapter 72 The Synthesis of the K- Ras -Derived Peptide
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    Chapter 75 Synthesis of a C-Terminal Fluorescein-Labeled 36-mer Peptide
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    Chapter 77 One-Dimensional Spatial Encoding: Split/Mix Synthetic Parallelism with Tag-Free Identification and Assays at the Speed of Light
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    Chapter 84 Mapping of Discontinuous Epitopes on FSH
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    Chapter 87 Screening and Synthesis of a Positional Scanning Library Based on the Bowman-Birk Reactive Site Loop
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    Chapter 88 A Bicyclic Peptide Template Useful for Solution-Phase Combinatorial Synthesis
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    Chapter 92 High Throughput Peptide Syntheses Generate Ligands for Proteomic Database
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    Chapter 93 MHC Ligand Motifs from Peptide Libraries: The Software EPIPREDICT
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    Chapter 96 Peptides as Drugs: Is There a Market?
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    Chapter 97 Solid-Phase Total Syntheses of Trunkamide A and Kahalalide F, Cyclic Peptides from Marine Origin
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    Chapter 98 Solid Phase Synthesis of Large Cyclic Peptides
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    Chapter 101 Ampullosporin Analogs: Solid Phase Synthesis, Conformational Studies, and Biological Activities
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    Chapter 102 Synthesis of Lanthionine-Containing Peptides on Solid Phase via an Orthogonal Protecting Group Strategy
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    Chapter 103 Systematic Solid Phase Synthesis of Linear Pseudooligolysines Containing Multiple Adjacent CH 2 NH Amide Bond Surrogates: Potential Agents for Gene Delivery
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    Chapter 104 Peptide Transformation and Synthesis of Oligopeptidomimetics
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    Chapter 110 Triphosgene as Peptide Coupling Reagent: Highly Efficient Total Synthesis of Cyclosporin O
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    Chapter 111 Synthesis of Ferrocene Linkers for Solid-Phase Synthesis of Peptides
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    Chapter 113 Structural Characterization of a Dibenzylated-CGRP(8–37), a Byproduct from N -α-Benzylation of CGRP(8–37)
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    Chapter 114 Polyamines as Intermediates for the Synthesis of Heterocyclic Compounds and Oligomeric Heterocyclic Compounds from Resin-Bound Polyamides
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    Chapter 115 Solid-Phase Synthesis of Substituted Dihydroimidazoles and Their Bis Analogs
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    Chapter 122 Oxidation of Threonine and Serine Residues on Solid-Phase: Pyrazine Formation by Dess-Martin Periodinane Oxidation
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    Chapter 123 A Novel Solid Phase Approach to Thioether Cyclized Peptides: Discovery of Mouse Melanocortin-1 Receptor Agonists
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    Chapter 124 Bifurcated Dipeptide Schiff Bases as Ligands for Enantioselective Catalysis: Micro-Metalloenzymes
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    Chapter 125 Recent Advances in the Solid-Phase Synthesis of Long-Chain β-Peptides
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    Chapter 127 N to C Solid Phase Organic Synthesis of Peptidic and Peptidomimetic Derivatives Using 9-Fluorenylmethyl Esters
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    Chapter 128 A New Method to Quantify the Swelling Properties of Polymer Beads Used in Solid Phase Peptide Synthesis (SPPS)
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    Chapter 129 A Novel High Throughput Analysis of Total Nitrogen Content by a Colorimetric Method
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    Chapter 130 Conformational Studies of Cyclotetrapeptides [Xaa-D-Ala] 2 by NMR, CD and Molecular Modeling
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    Chapter 135 Coupled Plasmon Waveguide Resonance Studies of Agonist/Antagonist Binding to the Human δ-Opioid Receptor Provide New Structural Insights Into the Three-State Model for Receptor-Ligand Interactions
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    Chapter 139 Solution Structure of Oligopeptides-Copper(II) Complexes
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    Chapter 140 Development of Antibodies Against Conjugated Benzophenone, as a Tool in Photoaffinity Crosslinking Studies
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    Chapter 142 NMR Structural Investigation of a β 3 -Dodecapeptide with Proteinogenic Side Chains in MeOH and Water
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    Chapter 145 High Throughput Validation and Quantitation of Synthetic Peptides via LC-MS
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    Chapter 147 Role of Residues in Position 2 and 7 on the Conformation of the N-Terminal Apamin Loop
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    Chapter 149 Molecular Modeling Study of the β-Turn-Type Reversals Involved in 3D Structure of IFABP
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    Chapter 152 The Influence of the Surrounding Media on the Structural Propensities of Amino Acid Residues in Proteins
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    Chapter 153 CD Evidence of the Conformational Transitions in rMOG[1–125] in the Presence of Membrane Mimicking Detergents
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    Chapter 157 Human Relaxin Chain Combination and Folding
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    Chapter 159 Introduction of Temperature-Sensitive Elastin-Based Switches to Stabilize Globular Proteins
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    Chapter 160 A Short-Range Interaction of the cis-trans Urea Motif in Ureapeptides
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    Chapter 162 The Determination of Helix Stability Coefficients Using D-Amino Acid Substitutions in the non-Polar Face of an Amphipathic α-Helical Model Peptide
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    Chapter 163 NMR-Based Studies of a Collagenous Substrate of Collagenase
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    Chapter 164 Conformational Analysis of Model Polypeptides Having Repetitive Xaa-Pro Sequences
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    Chapter 165 The Role of Unstructured Highly Charged Regions on the Stability and Specificity of Dimerization of Two-Stranded α-Helical Coiled-Coils: Neck Region of Kinesin-Like Motor Protein Kif3A
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    Chapter 167 Template-Assisted Stabilization of a Short HIV-1 gp41 Inner-Core Coiled-Coil Peptide
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    Chapter 170 Peptides Based on Daf, the First Rigid, Transition-Metal Receptor: C α,α -Disubstituted Glycine
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     Chapter 171 Allyl-Based, C α -Methylated α-Amino Acids in the Side-Chain to Side-Chain Ring-Closing Metathesis Reaction of β-Turn/3 10 -Helical Peptides
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     Chapter 172 Synthesis and Conformational Analysis of Polypeptides Having Repetitive Xaa-Pro-Pro Sequences
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     Chapter 174 Lactam-Bridged and Disulfide-Bridged Peptide Mimic of a Stable α-Helical Folded Protein
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     Chapter 177 Folding of β- and γ-Peptides — the Influence of Substitution Patterns on the Formation of Secondary Structures
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     Chapter 178 The β-Methyne of Ile3 in the Propeptide Region of Prouroguanylin is Crucial for Chaperone Function in the Folding of the Mature Peptide, Uroguanylin
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     Chapter 184 Peptide Models for Studying Autonomous Folding of Subdomain Sections of Protein Molecules
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     Chapter 185 Towards New Designed Proteins: Oxime Ligation of Core Modules
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     Chapter 187 Direct Observation of Backbone Hydrogen Bonding in the Folding Transition of Chymotrypsin Inhibitor 2 (CI2)
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     Chapter 191 Synthesis and Characterization of the Pain-Killing Peptide Grammostola spatulata Analgesic Factor (GsAF-1) Containing Three Disulfide Bonds
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     Chapter 194 Electrostatic and Hydrophobic Nature of the Binding of Gelsolin 135–142 and Gelsolin 150–169 Fragments to the PIP2-Containing Lipid Bilayer
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     Chapter 195 Prediction of Antibody Complexes with Rationally-Designed and Library-Derived Cyclic Peptides: A Computer Modeling Study
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     Chapter 197 Theoretical Design of α-Hairpin Structures
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     Chapter 199 DARWINIZER® — a Computer Based Method for Peptide and Peptidomimetics Design
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     Chapter 205 Amphipathic Stabilization of the 3 10 -/α-Helix Equilibrium in Synthetic Peptides Rich in C α , C α -Disubstituted Glycines
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     Chapter 206 Design, Synthesis and Characterization of Novel Scaffold-Assembled Collagen Mimetics
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     Chapter 208 Site Specificity Metal Binding Affinity in C-Terminal of Calmodulin
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     Chapter 209 A Cassette Ribonuclease: Site Selective Cleavage of RNA by a Ribonuclease S-Bearing RNA-Recognition Segment
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     Chapter 211 New Foldamers: Rigid Peptides with an Alternating cis-trans Amide Sequence
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     Chapter 212 Design, Synthesis, and Conformational Studies of Short Peptides Containing C αα -Dipropylglycine and Dibenzylglycine
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     Chapter 213 Bromo Tryptophan Based Antisickling Peptides: Design, Synthesis and Evaluation
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     Chapter 214 Synthesis, Redox and Structural Properties of Cystine-Cyclopeptides Containing the Active-Site of the Thioredoxin Superfamily
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     Chapter 216 Homostranded and Heterostranded α-Helical Templates for Combinatorial Library Display: Differences in Stability and Solubility
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     Chapter 217 Synthesis and Solution Structures of Cyclic Hexapeptides Cyclo(Pro-Leu-Xxx) 2
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     Chapter 218 Functional and Structural Comparisons of Linear and Dendritic Arrays of Polypeptides
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     Chapter 221 Relationship Between Amphipathic Secondary Structure and Activity in Model Linear Cationic Antimicrobial Peptides
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     Chapter 225 Antimicrobial and Chemotactic Activities of ω-Conotoxin Cyclic Analogues
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     Chapter 230 Variation in Ring Size of Cyclic Antimicrobial Peptides Results in Diversity and Selectivity of Biological Activity
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     Chapter 231 α-Helical Glycopeptide Analgesics: β-Endorphin Mimics with Good in vivo Potency
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     Chapter 233 Glycation of Leucine-Enkephalin: Imidazolidinones and Amadori Compounds
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     Chapter 234 Solid-Phase Synthesis of Thio-Linked C-Terminal Glycopeptides via a Mitsunobu Reaction
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     Chapter 236 Synthesis of Peptide- and Glycopeptide-Conjugates for Specific Drug Targeting
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     Chapter 238 Short Analogues of the Lipopeptaibol Trichogin GA IV
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     Chapter 239 Dinuclear Zinc(II) Complexes of Linear and Cyclic Peptides Containing Two Bis(2-pyridylmethyl)amino Groups as Catalysts for Hydrolysis of RNA Model Substrate
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     Chapter 240 Construction of RNA-Binding Proteins Having Nucleobase Amino Acids Based on HIV-1 Nucleocapsid Protein
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     Chapter 241 Screening of Peptides that Control Interaction Between Nucleobases from Peptide Libraries Based on Loop Structures
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     Chapter 242 Preparation of a Site-Specifically Labeled Fluorescent Chemokine by Chemical Synthesis
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     Chapter 243 Synthesis, Characterization, and Calorimetric Studies of a Series of Novel Bioconjugates for Selective Targeting of Microbubbles to GPIIbIIIa Receptors on Vascular Thrombi
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     Chapter 244 Energy and Electron Transfer Systems Built in Dendritic Poly(L-lysine)s
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     Chapter 248 Prime Site Binding Inhibitors of the Hepatitis C Virus NS3/4A Serine Protease
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     Chapter 250 Design and Synthesis of Novel Matrix Metalloproteinase Inhibitors
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     Chapter 252 Peptide Inhibitors of α-Amylase Based on Tendamistat: Synthesis and Kinetic Studies
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     Chapter 253 Structural Studies of the Complex Between Decapeptide Inhibitors and the Serine Protease NS3/4A of Hepatitis C Virus
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     Chapter 254 Synthesis and Activity of a Small Cyclic Protease Inhibitor from Sunflower Seeds, SFTI-1
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     Chapter 255 Different Types of P1 Residues in Peptide-Based Inhibitors of Hepatitis C Virus Full-Length NS3 Protease
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     Chapter 260 Bicyclic Peptide Inhibitors of an Epithelial Cell-Derived Transmembrane Protease, Matriptase
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     Chapter 266 Triply-Templated Artificial β-Sheets
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     Chapter 267 Stepwise Peptide-Peptoid Transformation via SPOT Synthesis
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     Chapter 268 SPOT Synthesis of 1,3,5-Trisubstituted Hydantoins on Cellulose Membranes
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     Chapter 269 Synthesis and CD Spectra of β 2 -(3-Aza-peptides)
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     Chapter 272 Synthetic Approach to Dipeptide Mimetics Based on Aminoacyl Incorporation Reaction
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     Chapter 273 Convenient Conversion of Amino Acids to Their N -Hydroxylated Derivatives on a Solid Support: Synthesis of Hydroxamate-Based Pseudo-Peptides
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     Chapter 274 Peptide Bond Modification for Metal Coordination: 1. Metal-Binding Properties of Hydroxamate-Based Pseudo-Peptides
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     Chapter 275 Peptide Bond Modification for Metal Coordination: 2. Metal-Binding Properties of Peptide-Derived Pentaaza-Macrocyclic Templates
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     Chapter 276 Peptide Bond Modification for Metal Coordination: 3. Metal-Binding Properties of Phosphorus-Based Pseudo-peptides
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     Chapter 277 Mimicry of the Backbone and Side-Chain Geometry of Peptide Turns: Synthesis of Novel 4-Substituted Indolizidin-9-one Amino Acids
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     Chapter 280 Pyridine as a Tripeptidomimetic Scaffold
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     Chapter 282 Synthesis of Peptide Mimetics and Amino Acid Mimetics Bearing Aminoxy Instead of Amino Group
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     Chapter 285 Design, Synthesis and Modulation of Angiogenesis by Thrombin Receptor Non-Peptide Antagonists
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     Chapter 286 Development of Endomorphin Derivatives with Dual Functions and Studies on Their Three-Dimensional Structure
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     Chapter 287 Stereoselective Synthesis of Tyrψ[CH 2 O]Phe and Tyrψ[CH 2 O]Ile, Methylene-oxy Analogs of Oxytocin and [8-Arginine]Vasopressin
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     Chapter 288 Exploration of the DTrp-NMeLys Motif in the Search for Potent Somatostatin Antagonists
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     Chapter 289 Synthesis and Biological Evaluation of Mixed β 2 /β 3 -Dipeptides as Somatostatin Analogs
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     Chapter 290 Cyclic Peptides Related to Somatostatin Containing a Novel Imidazole Derived cis -Amide Mimetic
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     Chapter 291 Human Somatostatin Receptor Specificity of Backbone-Cyclic Analogs Containing Novel Sulfur Building Units
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     Chapter 295 Bicyclic β-Strand Templates: Epimerization and Biological Activity of Non-Electrophilic Serine Protease Inhibitors
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     Chapter 296 Design, Synthesis and Biological Evaluation of Pilicides: Inhibitors of Pilus Assembly in Pathogenic Bacteria
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     Chapter 297 Phenylahistin, a Small Dipeptidic Colchicine-Like Anti-Microtubule Agent: Total Synthesis and SAR Study of the Derivatives
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     Chapter 298 New Antiproliferative Agents from a Peptidomimetic Library
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     Chapter 302 Prodrug Forms of Peptidomimetic HIV Protease Inhibitors Using Intramolecular Cyclization Reaction
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     Chapter 307 Design, Synthesis and Biological Evaluation of Novel Non-Peptide Opioid Ligands for Human Pain
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     Chapter 308 Design and Synthesis of Novel Pure Motilin Antagonists
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     Chapter 310 A Potent Non-Peptide Inhibitor of Anthrax Lethal Factor
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     Chapter 311 Highly Potent Analogs of Human Parathyroid Hormone and Human Parathyroid Hormone-Related Protein
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     Chapter 312 Glucagon-Like Peptide-1 Analogs with Significantly Improved in vivo Activity
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     Chapter 318 Modifications of the Tic Residue in TIPP-Peptides
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     Chapter 319 Structure-Activity Relationships of Linear and Cyclic Nociceptin Analogs and Conformational Analysis by CD and NMR Spectroscopy
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     Chapter 320 Design and Synthesis of Dynorphin A-(1–11) Analogs with C-Terminal Modifications and Evaluation of their Opioid Activity
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     Chapter 322 Design and Synthesis of Bifunctional Peptides: Antagonists at CCKA/CCKB Receptors and Agonists at μ/δ Opioid Receptors
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     Chapter 325 Pseudoprolines for Studying Bioactive cis -Prolyl Conformations
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     Chapter 330 The Development of a Novel Highly Selective and Potent Agonist for Human Melanocortin 4 Receptor
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     Chapter 331 Synthesis and NMR Characterization of Melanin-Concentrating Hormone
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     Chapter 333 Development of a Human Growth Hormone Peptide Analogue AOD9604 into an Anti-Obesity Drug
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     Chapter 334 Rational Approach to Stable, Universal Somatostatin Analogues with Superior Therapeutic Potential
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     Chapter 336 Exploring the “Double-Ring” Motif in Bradykinin Antagonists
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     Chapter 338 Identification of Key-Residues of Urotensin II, a Potent Mammalian Vasoconstrictor
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     Chapter 339 Structure-Activity Studies on the Corticotropin Releasing Factor Antagonist Astressin, Minimal Sequence Necessary for Antagonistic Activity: Implications for a New Pharmacophoric Model
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     Chapter 340 Solid-Phase Synthesis and Radiolabeling of a Bombesin Peptide Analog for Diagnostic Imaging of Tumors: A Preliminary Report
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     Chapter 341 Investigation on the Structural Requirements for Binding Integrin α IIb β 3
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     Chapter 342 Linear and Cyclic Peptides for Integrin α v β 6 Inhibition
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     Chapter 346 Local Conformation Around Position 12 of the (1–34) Fragment of Parathyroid Hormone Probed by Substitution with Aib Residues
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     Chapter 349 A Novel Series of Growth Hormone Secretagogues
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     Chapter 351 Design of Cyclic α-Defensin Dimers as Channel Forming BuildingBlocks
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     Chapter 352 The Effect of Multiple Substitution of Aliphatic Amino Acids on the Structure, Function and Mode of Action of Lytic Peptides
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     Chapter 356 Low Molecular Weight Ψ[CH 2 NH] Pseudopeptides Yield Potent Antimicrobial Agents
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     Chapter 358 Structure-Function Relationship of Gramicidin-Alamethicin Hybrid Analogs
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     Chapter 359 Biaryl-Bridged Lipopeptides from Streptomyces sp. TÜ 6075
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     Chapter 360 Generation of Bioactive Peptides Derived from Caseins Using a Lactobacillus helveticus Strain
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     Chapter 361 Bioactive Peptides Produced by a Strain of Lactobacillus plantarum : Characterization and Partial Purification
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     Chapter 362 Stilboflavins, a Natural Peptaibol Library from the Mold Stilbella flavipes
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     Chapter 368 Synthesis and Pharmacological Activity of Superagonists of the ORL1 Receptor
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     Chapter 372 Effect of Deficiency of Cytochrome C Oxidase Assembly Peptide Cox17p on Mitochondrial Functions and Respiratory-Chain in Mice
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     Chapter 373 Circadian Rhythm Pacemaker Neuropeptide “PDF” in Nocturnal Insect Cricket Gryllus bimaculatus : cDNA Cloning, mRNA Expression, and Nuclear Localization
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     Chapter 377 HPLC Analysis, Modeling, and Biological Studies of Antiproliferative Heterocyclic Carboxamides
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     Chapter 379 Analysis and Evaluation of Rational Designed Calcium Binding Sites in CD2
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     Chapter 388 Primary Amphipathic Shuttle Peptides: Structural Requirements and Interactions with Model Membranes
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     Chapter 389 Synthesis, Purification, and Analysis of the Transmembrane Domain of Phospholamban
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     Chapter 390 Verification of a μ Opioid Receptor Model by Site-Directed Mutagenesis
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     Chapter 391 Solid-Phase Synthesis and Chemical Ligation of Transmembrane Segments of Rhodopsin
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     Chapter 393 Docking of Transmembrane Helices Into Four Helix Bundles in the High Affinity IgE Receptor
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     Chapter 394 Helical Net Plots and Surface Lipophilicity Mapping of Transmembrane Helices of Integral Membrane Proteins: Aids to 3D Structure Determination of Integral Membrane Proteins
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     Chapter 395 Studies on the Involvement of a His Residue of mt1 GPCR TM Helix V in the Interaction with Melatonin
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     Chapter 400 Role of the Water Medium in the Process of Signal Transmission from Peptides to Cellular Receptors
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     Chapter 402 Global Conformational Constraint in the Design of a Grb2 SH2 Domain Inhibitor
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     Chapter 403 Local Conformational Constraint in the Design of a Grb2 SH2 Domain Inhibitor
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     Chapter 405 Generation of Cellulose Membrane-Bound Peptides with Free C-Termini: A Useful Approach for PDZ Binding Studies
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     Chapter 406 A Focused Library Approach to PTP Inhibitor Discovery Predicated on the X-ray Structure of a PTPIB-Bound Lead Compound
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     Chapter 413 Regions of G-Protein-Coupled Receptors Identified by Multiple Sequence Alignment
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     Chapter 416 Structure-Activity Relationship Studies of New Cyclic MSH Analogues Using Cloned-Human Melanocortin Receptors Lead to Greater Selectivity and Inverse Agonists
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     Chapter 419 Synthesis, Bioactivity and Receptor Binding of Fluorescent NBD Labeled Analogs of the Tridecapeptide Mating Pheromone of Saccharomyces cerevisiae
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     Chapter 421 Characterizing the Interactions Between Cholecystokinin and the G-Protein Coupled Receptors CCK 1 and CCK 2 : An NMR-Based Study
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     Chapter 424 Receptor-Bound Conformation of α-Peptide of Transducin (G t ) is not Stabilized by a “π-Cation” Interaction but by Constrained Lactam Bridges Between Residues 341 and 350
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     Chapter 427 Specific Activation of the Insulin Receptor by the Transmembrane Domain Peptides
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     Chapter 430 Identification of Novel Ligands for Vasopressin V 2 Receptor from Positional Scanning Libraries
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     Chapter 431 Diversity Generation and Guest-Templated Self-Sorting in Dynamic Combinatorial Libraries
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     Chapter 432 NMR Studies of the Interaction of α-Bungarotoxin with a Mimotope of the Nicotinic Acetylcholine Receptor
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     Chapter 433 Selection of Antagonists of Fibroblast Growth Factor from a Phage-Display Peptide Library
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     Chapter 434 Peptide Carrier for Efficient Drug Transport Into Living Cells
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     Chapter 435 Design of Novel Cell Penetrating Peptides
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     Chapter 437 Liposaccharides: Utilisation for Peptide Delivery and for Enhancing Synthetic Peptide Immunogenicity
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     Chapter 438 Down-Regulation of HIV-1 Long Terminal Repeat Controlled Viral Transcription by DNA-Binding, Arginine-Rich Fusion Proteins Derived from HIV-1 TAT for the Direct Delivery into the Nucleus
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     Chapter 439 New Insights Into the Membrane Translocating Process of the Tat Peptide Used for Cellular Delivery of Various Biological Molecules
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     Chapter 440 DUROS® Osmotic Implant for the Delivery of Peptides and Proteins
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     Chapter 441 Utilization of ICAM-1 Peptide Conjugates for Drug Targeting to T-Cells
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     Chapter 443 Translocation of Various Arginine-Rich Peptides and the Potential of These Peptides as Carriers for Intracellular Protein Delivery
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     Chapter 445 Lipoamino Acid and Liposaccharide Conjugated Peptides: Enhancement of Bioavailability
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     Chapter 447 A Novel Class of Cell Permeable “Karyophilic” Peptides: NLS-Mediated Nuclear Import of Dermaseptin Derived Peptides in Intact Cells
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     Chapter 448 Characterization of Translocation Behavior of Arginine-Rich Membrane-Permeable Peptides
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     Chapter 449 Structure and Activity of the N-Terminal Peptides of HIV-1 Glycoprotein 41 Types M (Major) and O (Outlier)
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     Chapter 453 Alternate Aggregation Pathways of Alzheimer β-Amyloid Peptides
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     Chapter 459 Synthesis of Potent and Enzymatically Stable 4– 18 F-Benzoyl-NT(8–13) Analogs for Tumour Diagnosis Using PET
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     Chapter 460 In vivo Imaging of Protease Activity and Drug Screening
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     Chapter 461 Passive Repression of HIV-1 Long Terminal Repeat Enhancer Controlled Viral Transcription in HIV-1 Infected Cells by Cationic DNA-Binding Fusion Proteins
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     Chapter 464 Antibodies to Distinct Protein Epitopes from a Single Polyclonal Serum
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     Chapter 465 Epitope Mapping of Anti-Type I Collagen Crosslinked N-Telopeptide Antibody with Synthetic Peptides
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     Chapter 467 Folding and Peptide Binding of TPR Motifs from SGT
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     Chapter 468 CCT mRNA and CREB Phosphorylation Up Regulated by Peptide ZNC(C)PR in Rat Hippocampus
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     Chapter 470 Multivalent Vaccine Studies for HTLV-1 Associated Diseases
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     Chapter 473 Evaluation of Synergistic Interaction Between Cytokines and Peptide Epitope Vaccines in Protection Against HER-2 Expressing Lung Metastases
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     Chapter 474 Novel Classes of Neutrophil-Activating Peptides: Isolation and Their Physiological Significance
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     Chapter 475 Affinity of the HIV-1-Neutralizing Monoclonal Antibody 2F5 for gp41 ELDKWA Peptide Analogues
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     Chapter 477 Four-Segment Tandem Ligation of Proteins with Unusual Branched Architecture
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     Chapter 479 The Natural T-Helper Cell Epitope Repertoire is Unlikely to Contain Glycopeptides with Extended Carbohydrate Side-Chains
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     Chapter 482 B-Cell Linear Epitopes in the Conservative Regions of Hepatitis C Virus Envelope Glycoproteins
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     Chapter 484 Isolation, cDNA Cloning, and Chemical Synthesis of Oryctes rhinoceros Defensin
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     Chapter 485 Deamidation within a γ-Gliadin-Derived Peptide Enhances Its Recognition by Serum Antibodies of CD Patients
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     Chapter 494 Cuvette-Based Biosensors as Micropreparative Affinity Surfaces
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     Chapter 495 A Comprehensive Database of Protein-Protein Interactions
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     Chapter 498 TOAC Peptides as Catalysts of Enantioselective Oxidations