| Title |
Mechanisms of synaptic depression triggered by metabotropic glutamate receptors
|
|---|---|
| Published in |
Cellular and Molecular Life Sciences, August 2008
|
| DOI | 10.1007/s00018-008-8263-3 |
| Pubmed ID | |
| Authors |
C. Bellone, C. Lüscher, M. Mameli |
| Abstract |
Glutamate, by activation of metabotropic receptors (mGluRs), can lead to a reduction of synaptic efficacy at many synapses. These forms of synaptic plasticity are referred to as long-term depression (mGluR-LTD). We will distinguish between mGluR-LTD induced by pre- or postsynaptic receptors and mGluR-LTD induced by the locus of the expression mechanism of the synaptic depression. We will also review recent evidence that mGluR-mediated responses themselves are subject to depression, which may constitute a form of metaplasticity. |
Mendeley readers
The data shown below were compiled from readership statistics for 219 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 4 | 2% |
| Germany | 2 | <1% |
| Poland | 2 | <1% |
| France | 2 | <1% |
| Canada | 2 | <1% |
| United Kingdom | 2 | <1% |
| Kazakhstan | 1 | <1% |
| Brazil | 1 | <1% |
| Portugal | 1 | <1% |
| Other | 2 | <1% |
| Unknown | 200 | 91% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 64 | 29% |
| Researcher | 43 | 20% |
| Student > Master | 33 | 15% |
| Student > Bachelor | 15 | 7% |
| Professor | 12 | 5% |
| Other | 29 | 13% |
| Unknown | 23 | 11% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 90 | 41% |
| Neuroscience | 51 | 23% |
| Medicine and Dentistry | 22 | 10% |
| Biochemistry, Genetics and Molecular Biology | 13 | 6% |
| Psychology | 5 | 2% |
| Other | 7 | 3% |
| Unknown | 31 | 14% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 October 2020.
All research outputs
#7,845,540
of 23,794,258 outputs
Outputs from Cellular and Molecular Life Sciences
#1,655
of 4,151 outputs
Outputs of similar age
#30,958
of 85,081 outputs
Outputs of similar age from Cellular and Molecular Life Sciences
#17
of 33 outputs
Altmetric has tracked 23,794,258 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,151 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.0. This one is in the 38th percentile – i.e., 38% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 85,081 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 18th percentile – i.e., 18% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 33 others from the same source and published within six weeks on either side of this one. This one is in the 9th percentile – i.e., 9% of its contemporaries scored the same or lower than it.