Title |
Intensity of Rainfall and Severity of Melioidosis, Australia - Volume 9, Number 12—December 2003 - Emerging Infectious Diseases journal - CDC
|
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Published in |
Emerging Infectious Diseases, December 2003
|
DOI | 10.3201/eid0912.020750 |
Pubmed ID | |
Authors |
Bart J. Currie, Susan P. Jacups |
Abstract |
In a 12-year prospective study of 318 culture-confirmed cases of melioidosis from the Top End of the Northern Territory of Australia, rainfall data for individual patient locations were correlated with patient risk factors, clinical parameters, and outcomes. Median rainfall in the 14 days before admission was highest (211 mm) for those dying with melioidosis, in comparison to 110 mm for those surviving (p=0.0002). Median 14-day rainfall was also significantly higher for those with pneumonia. On univariate analysis, a prior 14-day rainfall of 125 mm was significantly correlated with pneumonia (odds ratio [OR] 1.70 [confidence interval [CI] 1.09 to 2.65]), bacteremia (OR 1.93 [CI 1.24 to 3.02]), septic shock (OR 1.94 [CI 1.14 to 3.29]), and death (OR 2.50 [CI 1.36 to 4.57]). On multivariate analysis, rainfall in the 14 days before admission was an independent risk factor for pneumonia (p=0.023), bacteremic pneumonia (p=0.001), septic shock (p=0.005), and death (p<0.0001). Heavy monsoonal rains and winds may cause a shift towards inhalation of Burkholderia pseudomallei. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Malaysia | 1 | 1% |
Rwanda | 1 | 1% |
United States | 1 | 1% |
Argentina | 1 | 1% |
Unknown | 90 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 17 | 18% |
Student > Master | 13 | 14% |
Student > Bachelor | 13 | 14% |
Researcher | 12 | 13% |
Other | 7 | 7% |
Other | 18 | 19% |
Unknown | 14 | 15% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 32 | 34% |
Agricultural and Biological Sciences | 16 | 17% |
Biochemistry, Genetics and Molecular Biology | 8 | 9% |
Immunology and Microbiology | 8 | 9% |
Engineering | 2 | 2% |
Other | 7 | 7% |
Unknown | 21 | 22% |