| Title |
Pathogenesis of ANCA-Associated Vasculitis
|
|---|---|
| Published in |
Current Rheumatology Reports, August 2012
|
| DOI | 10.1007/s11926-012-0286-y |
| Pubmed ID | |
| Authors |
Rodrigo Cartin-Ceba, Tobias Peikert, Ulrich Specks |
| Abstract |
Antineutrophil cytoplasmic autoantibodies (ANCA)-associated vasculitides (AAV) are a group of systemic vasculitis syndromes characterized by inflammation and necrosis of blood vessel walls. Genetic, epigenetic, and environmental factors contribute to the etiology and pathogenesis of AAV. On the basis of currently available clinical and experimental evidence, it is reasonable to believe that, in predisposed patients, different triggers can lead to the production of autoantibodies (ANCA) that, in the context of an inflammatory environment, can cause tissue inflammation and vascular injury. Several different pathways and mechanisms in the pathogenesis of AAV are described in this contemporary review. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 74 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Mexico | 1 | 1% |
| Uruguay | 1 | 1% |
| China | 1 | 1% |
| Unknown | 71 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 12 | 16% |
| Student > Master | 11 | 15% |
| Student > Postgraduate | 10 | 14% |
| Student > Bachelor | 9 | 12% |
| Student > Ph. D. Student | 5 | 7% |
| Other | 15 | 20% |
| Unknown | 12 | 16% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 43 | 58% |
| Agricultural and Biological Sciences | 4 | 5% |
| Immunology and Microbiology | 2 | 3% |
| Biochemistry, Genetics and Molecular Biology | 1 | 1% |
| Business, Management and Accounting | 1 | 1% |
| Other | 3 | 4% |
| Unknown | 20 | 27% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 June 2023.
All research outputs
#6,948,032
of 22,783,848 outputs
Outputs from Current Rheumatology Reports
#242
of 709 outputs
Outputs of similar age
#50,688
of 170,274 outputs
Outputs of similar age from Current Rheumatology Reports
#7
of 12 outputs
Altmetric has tracked 22,783,848 research outputs across all sources so far. This one has received more attention than most of these and is in the 68th percentile.
So far Altmetric has tracked 709 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.0. This one has gotten more attention than average, scoring higher than 64% of its peers.
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We're also able to compare this research output to 12 others from the same source and published within six weeks on either side of this one. This one is in the 41st percentile – i.e., 41% of its contemporaries scored the same or lower than it.