Title |
Antidepressant-associated maniform states in acute treatment of patients with bipolar-I depression
|
---|---|
Published in |
European Archives of Psychiatry and Clinical Neuroscience, December 1998
|
DOI | 10.1007/s004060050053 |
Pubmed ID | |
Authors |
R. Bottlender, Daniel Rudolf, Anton Strauss, Hans-Jürgen Möller |
Abstract |
Medical records of 158 patients with bipolar depression were analysed for the incidence of a switch from depression to maniform states (mania and hypomania). Relation to psychopharmacological treatment was investigated. Thirty-nine (25%) patients of the total sample had switched to a maniform state during the treatment period in the hospital. Among that group the phenomenon occurred in 23 patients (15%) as a hypomania and in 16 patients (10%) as a mania. Patients with a switch were significantly more often treated with tricyclic antidepressants (TCA) than patients without switch (79.5% vs 51.3%). Mood stabilising medication might reduce the risk for switching, especially in patients treated with TCA; however, it seems not totally sufficient, since 59% of the switched patients received mood stabilisers. The switch phenomenon was not associated with sociodemographic or clinical data. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 33% |
Unknown | 2 | 67% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 2 | 67% |
Scientists | 1 | 33% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
New Zealand | 1 | 5% |
Unknown | 20 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Professor | 4 | 19% |
Researcher | 4 | 19% |
Student > Master | 3 | 14% |
Student > Bachelor | 2 | 10% |
Student > Ph. D. Student | 2 | 10% |
Other | 3 | 14% |
Unknown | 3 | 14% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 6 | 29% |
Psychology | 4 | 19% |
Neuroscience | 2 | 10% |
Agricultural and Biological Sciences | 2 | 10% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 5% |
Other | 2 | 10% |
Unknown | 4 | 19% |