| Title |
Parkinson’s disease: oxidative stress and therapeutic approaches
|
|---|---|
| Published in |
Neurological Sciences, March 2010
|
| DOI | 10.1007/s10072-010-0245-1 |
| Pubmed ID | |
| Authors |
Sankar Surendran, Srinivasagam Rajasankar |
| Abstract |
Parkinson's disease (PD) is a neurodegenerative disorder, caused by reduced levels of catecholamines and oxidative stress. Symptoms seen in the disease include tremor, rigidity, bradykinesia and postural disability. Oxidative stress plays a key role in neurodegeneration and motor abnormalities seen in PD. Altered levels of the protein caused by these changes lead to defective ubiquitin-proteasome pathway. Neurodegeneration seen in PD and Canavan disease has a common mechanism. Recent studies suggest that herbal medicines can improve molecular changes and motor functions seen in PD. |
Mendeley readers
The data shown below were compiled from readership statistics for 84 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Portugal | 1 | 1% |
| Bangladesh | 1 | 1% |
| Brazil | 1 | 1% |
| Czechia | 1 | 1% |
| Spain | 1 | 1% |
| Unknown | 79 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 12 | 14% |
| Student > Bachelor | 11 | 13% |
| Student > Master | 10 | 12% |
| Researcher | 6 | 7% |
| Student > Doctoral Student | 5 | 6% |
| Other | 14 | 17% |
| Unknown | 26 | 31% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 14 | 17% |
| Medicine and Dentistry | 10 | 12% |
| Neuroscience | 9 | 11% |
| Pharmacology, Toxicology and Pharmaceutical Science | 8 | 10% |
| Biochemistry, Genetics and Molecular Biology | 5 | 6% |
| Other | 10 | 12% |
| Unknown | 28 | 33% |