Title |
Lanostane triterpenoids from Fomitopsis officinalis and their trypanocidal activity
|
---|---|
Published in |
Journal of Natural Medicines, February 2018
|
DOI | 10.1007/s11418-018-1182-1 |
Pubmed ID | |
Authors |
Shinen Naranmandakh, Toshihiro Murata, Batsukh Odonbayar, Keisuke Suganuma, Javzan Batkhuu, Kenroh Sasaki |
Abstract |
Fomitopsis officinalis is a medicinal fungus, known as 'Agarikon', and is used traditionally in the treatment of asthma and rheumatism in Mongolia. The investigation of the chemical constituents of F. officinalis led to the isolation of 4 new lanostane triterpenoids together with 4 known triterpenoids. Inhibitory activity against Trypanosoma congolense, which causes fatal diseases in animals including livestock, was estimated for the isolated compounds. Compounds 2-5 and 8 exhibited moderate inhibition activities with IC50 values ranging from 7.0-27.1 µM. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Practitioners (doctors, other healthcare professionals) | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 23 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 23 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 4 | 17% |
Student > Bachelor | 4 | 17% |
Student > Ph. D. Student | 3 | 13% |
Student > Doctoral Student | 2 | 9% |
Researcher | 2 | 9% |
Other | 6 | 26% |
Unknown | 2 | 9% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 5 | 22% |
Agricultural and Biological Sciences | 4 | 17% |
Chemistry | 4 | 17% |
Medicine and Dentistry | 2 | 9% |
Neuroscience | 2 | 9% |
Other | 2 | 9% |
Unknown | 4 | 17% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 February 2018.
All research outputs
#18,585,544
of 23,020,670 outputs
Outputs from Journal of Natural Medicines
#303
of 533 outputs
Outputs of similar age
#328,238
of 437,836 outputs
Outputs of similar age from Journal of Natural Medicines
#24
of 34 outputs
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