| Title |
Blood pressure targets in type 2 diabetes. Evidence against or in favour of an aggressive approach
|
|---|---|
| Published in |
Diabetologia, January 2018
|
| DOI | 10.1007/s00125-017-4537-3 |
| Pubmed ID | |
| Authors |
Giuseppe Mancia, Guido Grassi |
| Abstract |
When associated with high blood pressure, type 2 diabetes mellitus is characterised by a high risk of adverse cardiovascular (CV) and renal outcomes. However, both can be effectively reduced by antihypertensive treatment. Current guidelines on the treatment of hypertension emphasize the need to effectively treat high blood pressure in diabetic individuals, but their recommendations differ in terms of the optimal target blood pressure value to aim for in order to maximise CV and renal protection. In some guidelines the recommended target blood pressure values are <140/90 mmHg (systolic/diastolic), whereas in others, blood pressure values close or even less than 130/80 mmHg are recommended. This paper will discuss the evidence for and against a conservative or more aggressive blood pressure target for treated diabetic hypertensive individuals based on the evidence provided by randomised trials, trial meta-analyses and large observational studies. Based on the available evidence, it appears that blood pressure targets will probably have to be lower than <140/90 mmHg, and that values approaching 130/80 mmHg should be recommended. However, evidence in favour of even lower systolic values, i.e. <130 mmHg, is limited and is definitively against a reduction to <120 mmHg. |
X Demographics
The data shown below were collected from the profiles of 38 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 7 | 18% |
| Spain | 6 | 16% |
| India | 2 | 5% |
| United States | 1 | 3% |
| Netherlands | 1 | 3% |
| Chile | 1 | 3% |
| Canada | 1 | 3% |
| Israel | 1 | 3% |
| Bulgaria | 1 | 3% |
| Other | 2 | 5% |
| Unknown | 15 | 39% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 28 | 74% |
| Practitioners (doctors, other healthcare professionals) | 7 | 18% |
| Scientists | 2 | 5% |
| Science communicators (journalists, bloggers, editors) | 1 | 3% |
Mendeley readers
The data shown below were compiled from readership statistics for 49 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 49 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Other | 6 | 12% |
| Student > Ph. D. Student | 5 | 10% |
| Researcher | 5 | 10% |
| Professor | 4 | 8% |
| Student > Bachelor | 4 | 8% |
| Other | 12 | 24% |
| Unknown | 13 | 27% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 19 | 39% |
| Biochemistry, Genetics and Molecular Biology | 4 | 8% |
| Nursing and Health Professions | 3 | 6% |
| Agricultural and Biological Sciences | 3 | 6% |
| Pharmacology, Toxicology and Pharmaceutical Science | 2 | 4% |
| Other | 2 | 4% |
| Unknown | 16 | 33% |
Attention Score in Context
This research output has an Altmetric Attention Score of 34. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 August 2019.
All research outputs
#1,192,283
of 25,732,188 outputs
Outputs from Diabetologia
#632
of 5,376 outputs
Outputs of similar age
#27,621
of 452,662 outputs
Outputs of similar age from Diabetologia
#16
of 66 outputs
Altmetric has tracked 25,732,188 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 95th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 5,376 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 24.7. This one has done well, scoring higher than 88% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 452,662 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 93% of its contemporaries.
We're also able to compare this research output to 66 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 75% of its contemporaries.