Title |
Proton therapy for tumors of the skull base
|
---|---|
Published in |
Strahlentherapie und Onkologie, June 1999
|
DOI | 10.1007/bf03038890 |
Pubmed ID | |
Authors |
John E. Munzenrider, Norbert J. Liebsch |
Abstract |
Charged particle beams are ideal for treating skull base and cervical spine tumors: dose can be focused in the target, while achieving significant sparing of the brain, brain stem, cervical cord, and optic nerves and chiasm. For skull base tumors, 10-year local control rates with combined proton-photon therapy are highest for chondrosarcomas, intermediate for male chordomas, and lowest for female chordomas (94%, 65%, and 42%, respectively). For cervical spine tumors, 10-year local control rates are not significantly different for chordomas and chondrosarcomas (54% and 48%, respectively), nor is there any difference in local control between males and females. Observed treatment-related morbidity has been judged acceptable, in view of the major morbidity and mortality which accompany uncontrolled tumor growth. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 1% |
Germany | 1 | 1% |
Belgium | 1 | 1% |
Unknown | 79 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 17 | 21% |
Student > Postgraduate | 11 | 13% |
Student > Ph. D. Student | 9 | 11% |
Other | 7 | 9% |
Student > Master | 7 | 9% |
Other | 18 | 22% |
Unknown | 13 | 16% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 36 | 44% |
Neuroscience | 8 | 10% |
Physics and Astronomy | 8 | 10% |
Agricultural and Biological Sciences | 3 | 4% |
Engineering | 3 | 4% |
Other | 6 | 7% |
Unknown | 18 | 22% |