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Sarcopenia in cancer survivors is associated with increased cardiovascular disease risk

Overview of attention for article published in Supportive Care in Cancer, February 2018
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Title
Sarcopenia in cancer survivors is associated with increased cardiovascular disease risk
Published in
Supportive Care in Cancer, February 2018
DOI 10.1007/s00520-018-4083-7
Pubmed ID
Authors

Su Jung Lee, Yoon Jin Park, Kathleen B. Cartmell

Abstract

The aim of this study was to assess the association between sarcopenia and cardiovascular disease (CVD) risk in cancer survivors. We analyzed a consecutive series of 683 cancer survivors from the Korean National Health and Nutritional Exam Survey (2008-2011 years). Sarcopenia was defined as the appendicular skeletal muscle mass divided by weight (Kg) < 1 standard deviation below the sex-specific healthy population aged 20-39 years. CVD risks were assessed using the Framingham Risk Score (FRS), which were divided by tertile. Predictors of higher shift of FRS tertile by sex were calculated by stratified ordinal logistic regression analyses. Proportions of sarcopenia were 24.2% in males and 22.5% in females. Sarcopenic survivors were more likely to have a higher body mass index, waist circumference, blood pressure and fasting glucose level, and a lower high-density lipoprotein compared to those without sarcopenia. Sarcopenia was associated with a higher shift of FRS tertile (common odds ratio, 2.67; 95% confidence interval, 1.18-6.52, P < 0.001) in males. However, this association was not significant in female survivors. Sarcopenia was associated with an increased CVD risk in Korean male cancer survivors. Interventions to prevent sarcopenia may be necessary to improve cardiovascular burden in cancer survivors.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 53 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 53 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 12 23%
Student > Master 6 11%
Student > Doctoral Student 4 8%
Student > Ph. D. Student 4 8%
Researcher 3 6%
Other 4 8%
Unknown 20 38%
Readers by discipline Count As %
Medicine and Dentistry 14 26%
Nursing and Health Professions 7 13%
Agricultural and Biological Sciences 2 4%
Biochemistry, Genetics and Molecular Biology 2 4%
Materials Science 2 4%
Other 3 6%
Unknown 23 43%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 February 2018.
All research outputs
#18,585,544
of 23,020,670 outputs
Outputs from Supportive Care in Cancer
#3,647
of 4,643 outputs
Outputs of similar age
#327,805
of 437,329 outputs
Outputs of similar age from Supportive Care in Cancer
#71
of 92 outputs
Altmetric has tracked 23,020,670 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,643 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.7. This one is in the 12th percentile – i.e., 12% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 437,329 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 14th percentile – i.e., 14% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 92 others from the same source and published within six weeks on either side of this one. This one is in the 14th percentile – i.e., 14% of its contemporaries scored the same or lower than it.