Title |
Pyoverdines: pigments, siderophores and potential taxonomic markers of fluorescent Pseudomonas species
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Published in |
Archives of Microbiology, September 2000
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DOI | 10.1007/s002030000188 |
Pubmed ID | |
Authors |
Jean-Marie Meyer |
Abstract |
Pyoverdine, the yellow-green, water-soluble, fluorescent pigment of the fluorescent Pseudomonas species, is a powerful iron(III) scavenger and an efficient iron(III) transporter. As a fluorescent pigment, it represents a ready marker for bacterial differentiation and, as a siderophore, it plays an important physiological function in satisfying the absolute iron requirement of these strictly aerobic bacteria. Close to 40 structurally different pyoverdines have been identified to date, each characterized by a different peptidic part of the molecule and by a very narrow specificity as an iron transporter for Pseudomonas species, usually restricted to the producer strain or to strains producing an identical compound. Cross-reactivity does occur, however, for pyoverdines exhibiting partial identity at the peptide chain level, suggesting some information on the receptor-recognition site of the molecule. With the recent description of an operonic cluster of four genes involved in the synthesis of the chromophoric part of the molecule, a total of seven pyoverdine biosynthetic genes have been identified so far in Pseudomonas aeruginosa PAO1. Although the precise function of the gene products needs further clarification, a biosynthetic pathway based on a multienzyme thiotemplate mechanism allowing a step-by-step synthesis of the whole chromopeptide molecule can be postulated. A promising future is expected from recent developments which indicate that pyoverdines might be considered as potent and easy-to-handle taxonomic markers for the fluorescent species of the genus Pseudomonas. |
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Geographical breakdown
Country | Count | As % |
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United Kingdom | 2 | <1% |
Germany | 1 | <1% |
India | 1 | <1% |
Brazil | 1 | <1% |
Slovenia | 1 | <1% |
United States | 1 | <1% |
Unknown | 272 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 61 | 22% |
Student > Bachelor | 44 | 16% |
Student > Master | 39 | 14% |
Researcher | 32 | 11% |
Student > Doctoral Student | 17 | 6% |
Other | 35 | 13% |
Unknown | 51 | 18% |
Readers by discipline | Count | As % |
---|---|---|
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Biochemistry, Genetics and Molecular Biology | 44 | 16% |
Immunology and Microbiology | 18 | 6% |
Chemistry | 18 | 6% |
Medicine and Dentistry | 7 | 3% |
Other | 24 | 9% |
Unknown | 55 | 20% |