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Effect of water and ionic liquids on biomolecules

Overview of attention for article published in Biophysical Reviews, February 2018
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Title
Effect of water and ionic liquids on biomolecules
Published in
Biophysical Reviews, February 2018
DOI 10.1007/s12551-018-0399-2
Pubmed ID
Authors

Debasis Saha, Arnab Mukherjee

Abstract

The remarkable progress in the field of ionic liquids (ILs) in the last two decades has involved investigations on different aspects of ILs in various conditions. The nontoxic and biocompatible nature of ILs makes them a suitable substance for the storage and application of biomolecules. In this regard, the aqueous IL solutions have attracted a large number of studies to comprehend the role of water in modulating various properties of biomolecules. Here, we review some of the recent studies on aqueous ILs that concern the role of water in altering the behavior of ILs in general and in case of biomolecules solvated in ILs. The different structural and dynamic effects caused by water have been highlighted. We discuss the different modes of IL interaction that are responsible for stabilization and destabilization of proteins and enzymes followed by examples of water effect on this. The role of water in the case of nucleic acid storage in ILs, an area which has mostly been underrated, also has been emphasized. Our discussions highlight the fact that the effects of water on IL behavior are not general and are highly dependent on the nature of the IL under consideration. Overall, we aim to draw attention to the significance of water dynamics in the aqueous IL solutions, a better understanding of which can help in developing superior storage materials for application purposes.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 65 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 65 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 18 28%
Student > Master 10 15%
Researcher 8 12%
Student > Bachelor 6 9%
Student > Doctoral Student 4 6%
Other 3 5%
Unknown 16 25%
Readers by discipline Count As %
Chemistry 17 26%
Biochemistry, Genetics and Molecular Biology 14 22%
Chemical Engineering 5 8%
Physics and Astronomy 3 5%
Engineering 2 3%
Other 4 6%
Unknown 20 31%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 February 2018.
All research outputs
#20,462,806
of 23,020,670 outputs
Outputs from Biophysical Reviews
#704
of 799 outputs
Outputs of similar age
#377,296
of 439,449 outputs
Outputs of similar age from Biophysical Reviews
#15
of 27 outputs
Altmetric has tracked 23,020,670 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 799 research outputs from this source. They receive a mean Attention Score of 2.7. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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We're also able to compare this research output to 27 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.