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Age estimation based on aspartic acid racemization in dentine: what about caries-affected teeth?

Overview of attention for article published in International Journal of Legal Medicine, August 2017
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Title
Age estimation based on aspartic acid racemization in dentine: what about caries-affected teeth?
Published in
International Journal of Legal Medicine, August 2017
DOI 10.1007/s00414-017-1667-6
Pubmed ID
Authors

Nazan Sirin, Christian Matzenauer, Alexandra Reckert, Stefanie Ritz-Timme

Abstract

Age estimation based on aspartic acid racemization (AAR) in dentine is one of the most precise methods in adult age. Caries induces protein degradation and may have an impact on the kinetics of AAR in dentine. We systematically examined standardized prepared dentine samples from caries-affected teeth to clarify the question, if caries-affected teeth should not be used for age estimation based on AAR at all, or if the analysis of dentine samples from such teeth may be useful after removal of the caries-affected tissue according to clinical standards. Our results suggest that caries may lead to an extensive protein degradation even in macroscopically healthy-appearing dentine samples from caries-affected teeth and may significantly affect the precision of age estimation. To ensure the quality of age estimation based on AAR in forensic practice, we recommend using dentine samples from healthy teeth. If only caries-affected teeth are available, dentine samples from at least two teeth from the same individual should be analyzed as it seems unlikely that caries-induced protein degradation occurred with identical kinetics in two different teeth. In any case, results of the analysis of caries-affected teeth must be interpreted with caution.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 40 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 40 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 5 13%
Researcher 3 8%
Lecturer 3 8%
Student > Bachelor 3 8%
Student > Ph. D. Student 3 8%
Other 6 15%
Unknown 17 43%
Readers by discipline Count As %
Medicine and Dentistry 12 30%
Biochemistry, Genetics and Molecular Biology 3 8%
Unspecified 1 3%
Arts and Humanities 1 3%
Agricultural and Biological Sciences 1 3%
Other 3 8%
Unknown 19 48%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 February 2018.
All research outputs
#15,492,327
of 23,023,224 outputs
Outputs from International Journal of Legal Medicine
#973
of 2,087 outputs
Outputs of similar age
#200,403
of 319,215 outputs
Outputs of similar age from International Journal of Legal Medicine
#26
of 64 outputs
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So far Altmetric has tracked 2,087 research outputs from this source. They receive a mean Attention Score of 4.6. This one is in the 38th percentile – i.e., 38% of its peers scored the same or lower than it.
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