Title |
2017 PRETEXT: radiologic staging system for primary hepatic malignancies of childhood revised for the Paediatric Hepatic International Tumour Trial (PHITT)
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Published in |
Pediatric Radiology, February 2018
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DOI | 10.1007/s00247-018-4078-z |
Pubmed ID | |
Authors |
Alexander J. Towbin, Rebecka L. Meyers, Helen Woodley, Osamu Miyazaki, Christopher B. Weldon, Bruce Morland, Eiso Hiyama, Piotr Czauderna, Derek J. Roebuck, Greg M. Tiao |
Abstract |
Imaging is crucial in the assessment of children with a primary hepatic malignancy. Since its inception in 1992, the PRETEXT (PRE-Treatment EXTent of tumor) system has become the primary method of risk stratification for hepatoblastoma and pediatric hepatocellular carcinoma in numerous cooperative group trials across the world. The PRETEXT system is made of two components: the PRETEXT group and the annotation factors. The PRETEXT group describes the extent of tumor within the liver while the annotation factors help to describe associated features such as vascular involvement (either portal vein or hepatic vein/inferior vena cava), extrahepatic disease, multifocality, tumor rupture and metastatic disease (to both the lungs and lymph nodes). This manuscript is written by members of the Children's Oncology Group (COG) in North America, the International Childhood Liver Tumors Strategy Group (SIOPEL) in Europe, and the Japanese Study Group for Pediatric Liver Tumor (JPLT; now part of the Japan Children's Cancer Group) and represents an international consensus update to the 2005 PRETEXT definitions. These definitions will be used in the forthcoming Trial to Pediatric Hepatic International Tumor Trial (PHITT). |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 11 | 34% |
United Kingdom | 2 | 6% |
Canada | 2 | 6% |
Saudi Arabia | 1 | 3% |
Australia | 1 | 3% |
Algeria | 1 | 3% |
Finland | 1 | 3% |
Georgia | 1 | 3% |
Ecuador | 1 | 3% |
Other | 0 | 0% |
Unknown | 11 | 34% |
Demographic breakdown
Type | Count | As % |
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Practitioners (doctors, other healthcare professionals) | 14 | 44% |
Members of the public | 12 | 38% |
Scientists | 5 | 16% |
Science communicators (journalists, bloggers, editors) | 1 | 3% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 171 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Other | 23 | 13% |
Researcher | 20 | 12% |
Student > Postgraduate | 17 | 10% |
Student > Doctoral Student | 10 | 6% |
Professor | 10 | 6% |
Other | 37 | 22% |
Unknown | 54 | 32% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 96 | 56% |
Biochemistry, Genetics and Molecular Biology | 5 | 3% |
Nursing and Health Professions | 3 | 2% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 1% |
Immunology and Microbiology | 2 | 1% |
Other | 4 | 2% |
Unknown | 59 | 35% |