| Title |
Extensive polymorphism of ABO blood group gene: three major lineages of the alleles for the common ABO phenotypes
|
|---|---|
| Published in |
Human Genetics, June 1996
|
| DOI | 10.1007/bf02346189 |
| Pubmed ID | |
| Authors |
Kenichi Ogasawara, Makoto Bannai, Naruya Saitou, Ryuichi Yabe, Kenichi Nakata, Michiko Takenaka, Kiyoshi Fujisawa, Makoto Uchikawa, Yoshihide Ishikawa, Takeo Juji, Katsushi Tokunaga |
| Abstract |
Polymorphism of the ABO blood group gene was investigated in 262 healthy Japanese donors by a polymerase chain reactions-single-strand conformation polymorphism (PCR-SSCP) method, and 13 different alleles were identified. The number of alleles identified in each group was 4 for A1 (provisionally called ABO*A101, *A102, *A103 and *A104 according to the guidelines for human gene nomenclature), 3 for B (ABO*B101, *B102 and *B103), and 6 for O (ABO*O101, *O102, *O103, *O201, *O202 and *O203). Nucleotide sequences of the amplified fragments with different SSCP patterns were determined by direct sequencing. Phylogenetic network analysis revealed that these alleles could be classified into three major lineages, *A/*O1, *B and *O2. In Japanese, *A102 and *B101 were the predominant alleles with frequencies of 83% and 97% in each group, respectively, whereas in group O, two common alleles, *O101 (43%) and *O201 (53%), were observed. These results may be useful for the establishment of ABO genotyping, and these newly described ABO alleles would be advantageous indicators for population studies. |
Mendeley readers
The data shown below were compiled from readership statistics for 20 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| India | 1 | 5% |
| United States | 1 | 5% |
| Switzerland | 1 | 5% |
| Unknown | 17 | 85% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 4 | 20% |
| Student > Postgraduate | 4 | 20% |
| Student > Bachelor | 2 | 10% |
| Lecturer > Senior Lecturer | 2 | 10% |
| Student > Master | 2 | 10% |
| Other | 5 | 25% |
| Unknown | 1 | 5% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 6 | 30% |
| Agricultural and Biological Sciences | 6 | 30% |
| Medicine and Dentistry | 3 | 15% |
| Nursing and Health Professions | 1 | 5% |
| Unknown | 4 | 20% |
Attention Score in Context
This research output has an Altmetric Attention Score of 12. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 December 2022.
All research outputs
#2,557,090
of 23,460,553 outputs
Outputs from Human Genetics
#213
of 2,992 outputs
Outputs of similar age
#1,080
of 28,111 outputs
Outputs of similar age from Human Genetics
#1
of 35 outputs
Altmetric has tracked 23,460,553 research outputs across all sources so far. Compared to these this one has done well and is in the 88th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
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We're also able to compare this research output to 35 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 97% of its contemporaries.