| Title |
TNF-α acutely upregulates amylin expression in murine pancreatic beta cells
|
|---|---|
| Published in |
Diabetologia, November 2010
|
| DOI | 10.1007/s00125-010-1972-9 |
| Pubmed ID | |
| Authors |
K. Cai, D. Qi, O. Wang, J. Chen, X. Liu, B. Deng, L. Qian, X. Liu, Y. Le |
| Abstract |
Amylin, a secretory protein mainly produced by pancreatic beta cells, is elevated in the circulation of patients with diseases related to acute and chronic inflammation, including acute pancreatitis, pancreas graft rejection, obesity and insulin resistance. TNF-α is involved in these disorders. We investigated the effect of TNF-α on amylin levels and the underlying mechanisms, using murine pancreatic beta cell line MIN6 and pancreatic islets. |
Mendeley readers
The data shown below were compiled from readership statistics for 63 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 2% |
| Japan | 1 | 2% |
| Unknown | 61 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 14 | 22% |
| Researcher | 10 | 16% |
| Student > Bachelor | 8 | 13% |
| Student > Master | 8 | 13% |
| Student > Postgraduate | 5 | 8% |
| Other | 6 | 10% |
| Unknown | 12 | 19% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 18 | 29% |
| Biochemistry, Genetics and Molecular Biology | 13 | 21% |
| Agricultural and Biological Sciences | 9 | 14% |
| Pharmacology, Toxicology and Pharmaceutical Science | 3 | 5% |
| Nursing and Health Professions | 3 | 5% |
| Other | 2 | 3% |
| Unknown | 15 | 24% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 June 2022.
All research outputs
#7,413,245
of 22,663,969 outputs
Outputs from Diabetologia
#2,820
of 5,024 outputs
Outputs of similar age
#53,814
of 179,589 outputs
Outputs of similar age from Diabetologia
#15
of 34 outputs
Altmetric has tracked 22,663,969 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 5,024 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 22.6. This one is in the 19th percentile – i.e., 19% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 179,589 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 27th percentile – i.e., 27% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 34 others from the same source and published within six weeks on either side of this one. This one is in the 29th percentile – i.e., 29% of its contemporaries scored the same or lower than it.