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Mendeley readers
Attention Score in Context
| Title |
Human but not rat amylin shares neurotoxic properties with Aβ42 in long‐term hippocampal and cortical cultures
|
|---|---|
| Published in |
Febs Letters, May 2008
|
| DOI | 10.1016/j.febslet.2008.05.006 |
| Pubmed ID | |
| Authors |
Yun-An Lim, Lars M. Ittner, Yun Li Lim, Jürgen Götz |
| Abstract |
Type 2 diabetes mellitus (DM) and Alzheimer's disease (AD) share epidemiological and biochemical features. Both are characterized by insoluble protein aggregates with a fibrillar conformation--amylin in Type 2 DM pancreatic islets, and Abeta in AD brain. To determine whether amylin shares neurotoxic properties with Abeta, we incubated hippocampal and cortical neurons with Abeta42 and human amylin. Different from non-amyloidogenic rat amylin, both caused a dose-, time- and cell type-specific neurotoxicity supporting the notion of a similar toxic mechanism. Depending on the cell type, this finding is also supported by co-incubation of human amylin and Abeta. |
Mendeley readers
The data shown below were compiled from readership statistics for 40 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 40 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 10 | 25% |
| Student > Ph. D. Student | 9 | 23% |
| Student > Doctoral Student | 5 | 13% |
| Student > Master | 4 | 10% |
| Researcher | 2 | 5% |
| Other | 5 | 13% |
| Unknown | 5 | 13% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 8 | 20% |
| Neuroscience | 8 | 20% |
| Agricultural and Biological Sciences | 8 | 20% |
| Pharmacology, Toxicology and Pharmaceutical Science | 6 | 15% |
| Chemistry | 3 | 8% |
| Other | 3 | 8% |
| Unknown | 4 | 10% |
Attention Score in Context
This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 October 2021.
All research outputs
#5,452,627
of 25,394,764 outputs
Outputs from Febs Letters
#2,117
of 14,379 outputs
Outputs of similar age
#18,758
of 97,863 outputs
Outputs of similar age from Febs Letters
#7
of 46 outputs
Altmetric has tracked 25,394,764 research outputs across all sources so far. Compared to these this one has done well and is in the 75th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 14,379 research outputs from this source. They receive a mean Attention Score of 4.7. This one has gotten more attention than average, scoring higher than 70% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 97,863 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 72% of its contemporaries.
We're also able to compare this research output to 46 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 65% of its contemporaries.