Title |
An overview of hazard and risk assessment of the OECD high production volume chemical category—Long chain alcohols [C6–C22] (LCOH),
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Published in |
Ecotoxicology & Environmental Safety, November 2008
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DOI | 10.1016/j.ecoenv.2008.10.006 |
Pubmed ID | |
Authors |
Hans Sanderson, Scott E. Belanger, Peter R. Fisk, Christoph Schäfers, Gauke Veenstra, Allen M. Nielsen, Yutaka Kasai, Andreas Willing, Scott D. Dyer, Kathleen Stanton, Richard Sedlak |
Abstract |
This review summarizes the findings of the assessment report for the category, long chain alcohols (LCOH) with a carbon chain length range of C(6)-C(22) covering 30 substances, and >1.5million tonnes/year consumed globally. The category was evaluated under the Organization for Economic Co-operation and Development (OECD) high production volume chemicals program in 2006. The main findings of the assessment include: (1) no unacceptable human or environmental risks were identified; (2) these materials are rapidly and readily biodegradable; (3) a parabolic relationship was demonstrated between carbon chain length and acute and chronic aquatic toxicity; (4) category-specific (quantitative) structure-activity relationships were developed enabling prediction of properties across the entire category; (5) LCOH occur naturally in the environment in an equilibrium between synthesis and degradation; (6) industry coming together and sharing resources results in minimizing the need for additional animal tests, produces cost savings, and increases scientific quality of the assessment. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Spain | 1 | 3% |
Brazil | 1 | 3% |
Unknown | 32 | 94% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 5 | 15% |
Researcher | 5 | 15% |
Student > Bachelor | 5 | 15% |
Student > Master | 5 | 15% |
Student > Doctoral Student | 3 | 9% |
Other | 8 | 24% |
Unknown | 3 | 9% |
Readers by discipline | Count | As % |
---|---|---|
Environmental Science | 8 | 24% |
Chemistry | 4 | 12% |
Materials Science | 3 | 9% |
Chemical Engineering | 2 | 6% |
Agricultural and Biological Sciences | 2 | 6% |
Other | 10 | 29% |
Unknown | 5 | 15% |