Title |
Effect of oral intake of choline-stabilized orthosilicic acid on hair tensile strength and morphology in women with fine hair
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Published in |
Archives of Dermatological Research, October 2007
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DOI | 10.1007/s00403-007-0796-z |
Pubmed ID | |
Authors |
R. R. Wickett, E. Kossmann, A. Barel, N. Demeester, P. Clarys, D. Vanden Berghe, M. Calomme |
Abstract |
The appearance of hair plays an important role in people's overall physical appearance and self-perception. Silicon (Si) has been suggested to have a role in the formation of connective tissue and is present at 1-10 ppm in hair. Choline-stabilized orthosilicic acid ("ch-OSA") is a bioavailable form of silicon which was found to improve skin microrelief and skin mechanical properties in women with photoaged skin. The effect of ch-OSA on hair was investigated in a randomized, double blind, placebo-controlled study. Forty-eight women with fine hair were given 10 mg Si/day in the form of ch-OSA beadlets (n = 24) or a placebo (n = 24), orally for 9 months. Hair morphology and tensile properties were evaluated before and after treatment. Urinary silicon concentration increased significantly in the ch-OSA supplemented group but not in the placebo group. The elastic gradient decreased in both groups but the change was significantly smaller in the ch-OSA group (-4.52%) compared to placebo group (-11.9%). Break load changed significantly in the placebo group (-10.8%) but not in the ch-OSA supplemented group (-2.20%). Break stress and elastic modulus decreased in both groups but the change was smaller in the ch-OSA group. The cross sectional area increased significantly after 9 months compared to baseline in ch-OSA supplemented subjects but not in the placebo group. The change in urinary silicon excretion was significantly correlated with the change in cross sectional area. Oral intake of ch-OSA had a positive effect on tensile strength including elasticity and break load and resulted in thicker hair. |
X Demographics
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Hungary | 1 | 100% |
Demographic breakdown
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
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Australia | 1 | 1% |
Unknown | 99 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Master | 15 | 15% |
Researcher | 15 | 15% |
Student > Ph. D. Student | 9 | 9% |
Student > Bachelor | 8 | 8% |
Student > Postgraduate | 8 | 8% |
Other | 17 | 17% |
Unknown | 28 | 28% |
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Agricultural and Biological Sciences | 12 | 12% |
Biochemistry, Genetics and Molecular Biology | 10 | 10% |
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Pharmacology, Toxicology and Pharmaceutical Science | 6 | 6% |
Other | 14 | 14% |
Unknown | 33 | 33% |