| Title |
Exogenous gangliosides, neuronal plasticity and repair, and the neurotrophins
|
|---|---|
| Published in |
Cellular and Molecular Life Sciences, September 2005
|
| DOI | 10.1007/s00018-005-5188-y |
| Pubmed ID | |
| Authors |
I. Mocchetti |
| Abstract |
Gangliosides, a heterogeneous family of glycosphingolipids abundant in the brain, have been shown to affect neuronal plasticity during development, adulthood and aging. This review will examine old and recent evidence that exogenous gangliosides and in particular GM1, the prototype member of this family, exhibit multimodal neurotrophic effects. Since these compounds are a potential therapeutic tool for the treatment of various forms of acute or chronic neurodegenerative diseases, understanding the dynamic interplay of gangliosides and neuronal cells is essential in the effort to cure neurological disorders. Focus will be given to the novel and provocative hypothesis that gangliosides' neuroprotective properties may derive from their ability to mimic endogenous neurotrophic factors. |
Mendeley readers
The data shown below were compiled from readership statistics for 91 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Germany | 1 | 1% |
| Unknown | 90 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 25 | 27% |
| Student > Master | 15 | 16% |
| Researcher | 13 | 14% |
| Student > Bachelor | 9 | 10% |
| Student > Doctoral Student | 5 | 5% |
| Other | 12 | 13% |
| Unknown | 12 | 13% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 24 | 26% |
| Medicine and Dentistry | 14 | 15% |
| Biochemistry, Genetics and Molecular Biology | 10 | 11% |
| Chemistry | 9 | 10% |
| Neuroscience | 7 | 8% |
| Other | 15 | 16% |
| Unknown | 12 | 13% |
Attention Score in Context
This research output has an Altmetric Attention Score of 9. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 September 2023.
All research outputs
#3,907,044
of 26,017,215 outputs
Outputs from Cellular and Molecular Life Sciences
#752
of 6,041 outputs
Outputs of similar age
#8,276
of 73,678 outputs
Outputs of similar age from Cellular and Molecular Life Sciences
#3
of 25 outputs
Altmetric has tracked 26,017,215 research outputs across all sources so far. Compared to these this one has done well and is in the 83rd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 6,041 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.9. This one has done well, scoring higher than 84% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 73,678 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 84% of its contemporaries.
We're also able to compare this research output to 25 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 72% of its contemporaries.