| Title |
Diversity of Cl− Channels
|
|---|---|
| Published in |
Cellular and Molecular Life Sciences, November 2005
|
| DOI | 10.1007/s00018-005-5336-4 |
| Pubmed ID | |
| Authors |
M. Suzuki, T. Morita, T. Iwamoto |
| Abstract |
Cl(-) channels are widely found anion pores that are regulated by a variety of signals and that play various roles. On the basis of molecular biologic findings, ligand-gated Cl(-) channels in synapses, cystic fibrosis transmembrane conductors (CFTRs) and ClC channel types have been established, followed by bestrophin and possibly by tweety, which encode Ca(2+)-activated Cl(-) channels. The ClC family has been shown to possess a variety of functions, including stabilization of membrane potential, excitation, cell-volume regulation, fluid transport, protein degradation in endosomal vesicles and possibly cell growth. The molecular structure of Cl(-) channel types varies from 1 to 12 transmembrane segments. By means of computer-based prediction, functional Cl(-) channels have been synthesized artificially, revealing that many possible ion pores are hidden in channel, transporter or unidentified hydrophobic membrane proteins. Thus, novel Cl(-)-conducting pores may be occasionally discovered, and evidence from molecular biologic studies will clarify their physiologic and pathophysiologic roles. |
Mendeley readers
The data shown below were compiled from readership statistics for 117 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 3 | 3% |
| United States | 3 | 3% |
| Portugal | 2 | 2% |
| Netherlands | 1 | <1% |
| Australia | 1 | <1% |
| Czechia | 1 | <1% |
| Germany | 1 | <1% |
| Egypt | 1 | <1% |
| Sweden | 1 | <1% |
| Other | 0 | 0% |
| Unknown | 103 | 88% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 28 | 24% |
| Researcher | 25 | 21% |
| Student > Master | 16 | 14% |
| Professor | 7 | 6% |
| Student > Postgraduate | 7 | 6% |
| Other | 21 | 18% |
| Unknown | 13 | 11% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 52 | 44% |
| Biochemistry, Genetics and Molecular Biology | 15 | 13% |
| Chemistry | 11 | 9% |
| Medicine and Dentistry | 9 | 8% |
| Neuroscience | 6 | 5% |
| Other | 12 | 10% |
| Unknown | 12 | 10% |
Attention Score in Context
This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 January 2024.
All research outputs
#4,965,094
of 23,794,258 outputs
Outputs from Cellular and Molecular Life Sciences
#928
of 4,151 outputs
Outputs of similar age
#19,230
of 150,139 outputs
Outputs of similar age from Cellular and Molecular Life Sciences
#11
of 42 outputs
Altmetric has tracked 23,794,258 research outputs across all sources so far. Compared to these this one has done well and is in the 76th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,151 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.0. This one has gotten more attention than average, scoring higher than 70% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 150,139 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 81% of its contemporaries.
We're also able to compare this research output to 42 others from the same source and published within six weeks on either side of this one. This one is in the 47th percentile – i.e., 47% of its contemporaries scored the same or lower than it.