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Detection of dimethyl sulfone in the human brain by in vivo proton magnetic resonance spectroscopy

Overview of attention for article published in Magnetic Resonance Imaging (0730725X), January 2000
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Title
Detection of dimethyl sulfone in the human brain by in vivo proton magnetic resonance spectroscopy
Published in
Magnetic Resonance Imaging (0730725X), January 2000
DOI 10.1016/s0730-725x(99)00110-1
Pubmed ID
Authors

Stephen E Rosea, Jonathan B Chalk, Graham J Galloway, David M Doddrell

Abstract

We wish to report the detection of dimethyl sulfone (methylsulfonylmethane, C2H6O2S) in the brain of a normal 62-year-old male using in vivo proton magnetic resonance spectroscopy. The presence of this exogenous metabolite resulted from ingestion of a dietary supplement containing dimethyl sulfone. The concentration of this compound in the brain was measured to be 2.4 mmol, with a washout "half life" of approximately 7.5 days. The in vivo T1 and T2 relaxation times of dimethyl sulfone were measured to be 2180 ms and 385 ms, respectively. The concentration of major brain metabolites, namely N-acetylaspartate, total Creatine and Choline, and myo-Inositol were within normal limits.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 36 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 3%
Germany 1 3%
South Africa 1 3%
Switzerland 1 3%
Unknown 32 89%

Demographic breakdown

Readers by professional status Count As %
Researcher 8 22%
Student > Master 6 17%
Student > Bachelor 4 11%
Other 3 8%
Student > Ph. D. Student 3 8%
Other 6 17%
Unknown 6 17%
Readers by discipline Count As %
Agricultural and Biological Sciences 5 14%
Medicine and Dentistry 5 14%
Engineering 5 14%
Immunology and Microbiology 2 6%
Physics and Astronomy 2 6%
Other 10 28%
Unknown 7 19%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 December 2020.
All research outputs
#8,534,528
of 25,371,288 outputs
Outputs from Magnetic Resonance Imaging (0730725X)
#502
of 1,941 outputs
Outputs of similar age
#24,912
of 109,780 outputs
Outputs of similar age from Magnetic Resonance Imaging (0730725X)
#4
of 8 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,941 research outputs from this source. They receive a mean Attention Score of 3.7. This one is in the 39th percentile – i.e., 39% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 109,780 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 16th percentile – i.e., 16% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 8 others from the same source and published within six weeks on either side of this one. This one has scored higher than 4 of them.