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Mendeley readers
Attention Score in Context
| Title |
Identification of Microcephalin, a Protein Implicated in Determining the Size of the Human Brain
|
|---|---|
| Published in |
American Journal of Human Genetics, June 2002
|
| DOI | 10.1086/341283 |
| Pubmed ID | |
| Authors |
Andrew P. Jackson, Helen Eastwood, Sandra M. Bell, Jimi Adu, Carmel Toomes, Ian M. Carr, Emma Roberts, Daniel J. Hampshire, Yanick J. Crow, Alan J. Mighell, Gulshan Karbani, Hussain Jafri, Yasmin Rashid, Robert F. Mueller, Alexander F. Markham, C. Geoffrey Woods |
| Abstract |
Primary microcephaly (MIM 251200) is an autosomal recessive neurodevelopmental condition in which there is a global reduction in cerebral cortex volume, to a size comparable with that of early hominids. We previously mapped the MCPH1 locus, for primary microcephaly, to chromosome 8p23, and here we report that a gene within this interval, encoding a BRCA1 C-terminal domain-containing protein, is mutated in MCPH1 families sharing an ancestral 8p23 haplotype. This gene, microcephalin, is expressed in the developing cerebral cortex of the fetal brain. Further study of this and related genes may provide important new insights into neocortical development and evolution. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 210 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 3 | 1% |
| United Kingdom | 1 | <1% |
| Canada | 1 | <1% |
| Unknown | 205 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 40 | 19% |
| Student > Master | 30 | 14% |
| Researcher | 26 | 12% |
| Student > Bachelor | 24 | 11% |
| Professor > Associate Professor | 11 | 5% |
| Other | 39 | 19% |
| Unknown | 40 | 19% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 59 | 28% |
| Biochemistry, Genetics and Molecular Biology | 46 | 22% |
| Medicine and Dentistry | 16 | 8% |
| Neuroscience | 16 | 8% |
| Social Sciences | 6 | 3% |
| Other | 24 | 11% |
| Unknown | 43 | 20% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 June 2021.
All research outputs
#7,356,550
of 25,377,790 outputs
Outputs from American Journal of Human Genetics
#3,175
of 5,879 outputs
Outputs of similar age
#40,412
of 126,616 outputs
Outputs of similar age from American Journal of Human Genetics
#25
of 57 outputs
Altmetric has tracked 25,377,790 research outputs across all sources so far. This one has received more attention than most of these and is in the 69th percentile.
So far Altmetric has tracked 5,879 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 18.3. This one is in the 43rd percentile – i.e., 43% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 126,616 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 67% of its contemporaries.
We're also able to compare this research output to 57 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 50% of its contemporaries.