Chapter title |
RNA virus populations as quasispecies.
|
---|---|
Chapter number | 1 |
Book title |
Genetic Diversity of RNA Viruses
|
Published in |
Current topics in microbiology and immunology, January 1992
|
DOI | 10.1007/978-3-642-77011-1_1 |
Pubmed ID | |
Book ISBNs |
978-3-64-277013-5, 978-3-64-277011-1
|
Authors |
J. J. Holland, J. C. De La Torre, D. A. Steinhauer, Holland, J. J., Torre, J. C., Steinhauer, D. A., De La Torre, J. C. |
Abstract |
RNA virus mutation frequencies generally approach maximum tolerable levels, and create complex indeterminate quasispecies populations in infected hosts. This usually favors extreme rates of evolution, although periods of relative stasis or equilibrium, punctuated by rapid change may also occur (as for other life forms). Because complex quasispecies populations of RNA viruses arise probabilistically and differentially in every host, their compositions and exact roles in disease pathogenesis are indeterminate and their directions of evolution, and the nature and timing of "new" virus outbreaks are unpredictable. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Germany | 1 | 1% |
Pakistan | 1 | 1% |
Italy | 1 | 1% |
Spain | 1 | 1% |
United States | 1 | 1% |
Unknown | 92 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 21 | 22% |
Student > Ph. D. Student | 18 | 19% |
Student > Master | 8 | 8% |
Student > Doctoral Student | 7 | 7% |
Student > Bachelor | 7 | 7% |
Other | 25 | 26% |
Unknown | 11 | 11% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 44 | 45% |
Biochemistry, Genetics and Molecular Biology | 16 | 16% |
Immunology and Microbiology | 9 | 9% |
Veterinary Science and Veterinary Medicine | 6 | 6% |
Medicine and Dentistry | 5 | 5% |
Other | 5 | 5% |
Unknown | 12 | 12% |