| Title |
Steroid sulphatase in man: A non inactivated X-locus with partial gene dosage compensation
|
|---|---|
| Published in |
Human Genetics, February 1984
|
| DOI | 10.1007/bf00291559 |
| Pubmed ID | |
| Authors |
G. Lykkesfeldt, Anne E. Lykkesfeldt, N. E. Skakkeb�k |
| Abstract |
Steroid sulphatase (STS) activity was measured with two different steroid substrates in leucocytes from normal human males and females, from females heterozygous for STS deficiency and recessive X-linked ichthyosis, and from individuals with numerical X chromosome aberrations. The results indicate non-inactivation with a partial gene dosage compensation at the STS locus. It is estimated that STS loci on inactive X chromosomes express approximately 45% of the STS activity originating from STS loci on active X chromosomes. It is also demonstrated that 45,XO (Turner syndrome) and 47,XXY (Klinefelter syndrome) individuals have abnormal STS enzyme levels compared with normal women and men, respectively. |
Mendeley readers
The data shown below were compiled from readership statistics for 7 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 7 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 1 | 14% |
| Professor | 1 | 14% |
| Student > Ph. D. Student | 1 | 14% |
| Researcher | 1 | 14% |
| Professor > Associate Professor | 1 | 14% |
| Other | 0 | 0% |
| Unknown | 2 | 29% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 1 | 14% |
| Agricultural and Biological Sciences | 1 | 14% |
| Medicine and Dentistry | 1 | 14% |
| Neuroscience | 1 | 14% |
| Engineering | 1 | 14% |
| Other | 0 | 0% |
| Unknown | 2 | 29% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 July 2019.
All research outputs
#7,453,126
of 22,785,242 outputs
Outputs from Human Genetics
#933
of 2,951 outputs
Outputs of similar age
#6,514
of 35,512 outputs
Outputs of similar age from Human Genetics
#6
of 14 outputs
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So far Altmetric has tracked 2,951 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.2. This one is in the 20th percentile – i.e., 20% of its peers scored the same or lower than it.
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