| Title |
Physical activity and telomere length in American Indians: the Strong Heart Study
|
|---|---|
| Published in |
European Journal of Epidemiology, February 2018
|
| DOI | 10.1007/s10654-018-0363-2 |
| Pubmed ID | |
| Authors |
Amanda M. Fretts, Mihriye Mete, Barbara V. Howard, Lyle G. Best, David S. Siscovick, Sigal Eilat-Adar, Jinying Zhao |
| Abstract |
Telomere length, a marker of biological aging, has been associated with many chronic diseases, but its relations with physical activity remains unclear. The purpose of this study was to examine the association of objectively measured ambulatory activity with leukocyte telomere length (LTL), a marker of biological aging, among American Indians. This cross-sectional study included 2312 AI participants from the Strong Heart Family Study. Steps per day were measured using Accusplit AE120 pedometers. Quantitative PCR was used to measure LTL. Generalized estimating equations were used to examine the associations of steps per day with LTL. The median steps per day over a 1 week period was 5118 steps (interquartile range = 3163-7576 steps). Compared to participants in the lowest quartile of steps per day, participants in the upper three quartiles of steps per day had longer LTL: beta ± SE = 0.0195 ± 0.0144, 0.0273 ± 0.0139, and 0.0375 ± 0.0143 T/S ratio units longer (p trend = 0.010) after adjustment for potential confounders. These data suggest that ambulatory activity is associated with LTL. Further studies are needed to determine the mechanism by which ambulatory activity influences LTL. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Japan | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Practitioners (doctors, other healthcare professionals) | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 35 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 35 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 5 | 14% |
| Student > Ph. D. Student | 5 | 14% |
| Student > Doctoral Student | 4 | 11% |
| Student > Master | 4 | 11% |
| Lecturer > Senior Lecturer | 3 | 9% |
| Other | 3 | 9% |
| Unknown | 11 | 31% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 7 | 20% |
| Nursing and Health Professions | 5 | 14% |
| Biochemistry, Genetics and Molecular Biology | 4 | 11% |
| Sports and Recreations | 3 | 9% |
| Agricultural and Biological Sciences | 1 | 3% |
| Other | 4 | 11% |
| Unknown | 11 | 31% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 February 2018.
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#21,576,568
of 24,074,860 outputs
Outputs from European Journal of Epidemiology
#1,667
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#382,620
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Outputs of similar age from European Journal of Epidemiology
#27
of 28 outputs
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