| Title |
Peptide aptamers: powerful new tools for molecular medicine
|
|---|---|
| Published in |
Journal of Molecular Medicine, September 2000
|
| DOI | 10.1007/s001090000140 |
| Pubmed ID | |
| Authors |
Felix Hoppe-Seyler, Karin Butz |
| Abstract |
One of the major goals in molecular medicine is to understand the basis of human diseases at the molecular level and to translate this information into new strategies for diagnosis and therapy. Peptide aptamers represent a novel generation of molecules, which are selected for their intracellular binding to a given target protein. They are useful tools for basic science in blocking the intracellular function of a target protein with high specificity, thereby allowing the study of distinct physiological and pathological processes within living cells. In addition, peptide aptamers provide a basis for the development of novel diagnostic and therapeutic strategies, with implications for a broad variety of different disease entities, including metabolic disorders, infections, and cancer. |
Mendeley readers
The data shown below were compiled from readership statistics for 78 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Brazil | 2 | 3% |
| United States | 2 | 3% |
| India | 2 | 3% |
| Germany | 1 | 1% |
| Italy | 1 | 1% |
| Japan | 1 | 1% |
| China | 1 | 1% |
| Unknown | 68 | 87% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 20 | 26% |
| Researcher | 18 | 23% |
| Student > Bachelor | 12 | 15% |
| Student > Master | 6 | 8% |
| Student > Postgraduate | 4 | 5% |
| Other | 9 | 12% |
| Unknown | 9 | 12% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 28 | 36% |
| Chemistry | 15 | 19% |
| Biochemistry, Genetics and Molecular Biology | 11 | 14% |
| Engineering | 7 | 9% |
| Medicine and Dentistry | 4 | 5% |
| Other | 2 | 3% |
| Unknown | 11 | 14% |
Attention Score in Context
This research output has an Altmetric Attention Score of 15. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 October 2023.
All research outputs
#2,071,591
of 23,410,748 outputs
Outputs from Journal of Molecular Medicine
#50
of 1,568 outputs
Outputs of similar age
#1,567
of 37,503 outputs
Outputs of similar age from Journal of Molecular Medicine
#1
of 8 outputs
Altmetric has tracked 23,410,748 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 91st percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,568 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.3. This one has done particularly well, scoring higher than 96% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 37,503 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 95% of its contemporaries.
We're also able to compare this research output to 8 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them