Title |
Coronary Artery Calcium Scoring in Young Adults: Evidence and Challenges
|
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Published in |
Current Cardiology Reports, February 2018
|
DOI | 10.1007/s11886-018-0951-5 |
Pubmed ID | |
Authors |
Marwan Saad, Naga Venkata Pothineni, Joseph Thomas, Richa Parikh, Swathi Kovelamudi, Dina Elsayed, Ramez Nairooz, Frederick Feit |
Abstract |
This review aims to summarize the evidence and challenges of coronary artery calcium (CAC) scoring as a screening tool for coronary artery disease (CAD) in young adults. Several cohort studies have highlighted the value of CAC scoring in CAD risk assessment in young adults. The largest study to date is the Coronary Artery Risk Development in Young Adults (CARDIA) study. The study examined patients at 18-30 years of age and demonstrated that the presence of any degree of CAC was associated with a higher risk of coronary events compared to zero CAC, with an incremental increase in the risk of events with higher scores. However, it is important to note that 70% of patients screened had CAC = 0 at the age of 56. Despite the evidence that higher CAC score cutoff used in guidelines for predicting cardiovascular risk may be "falsely reassuring," however, mass screening of young adults using CAC score may be challenging. The development of prediction tools and scoring systems to identify patients at higher risk of developing CAC based on known CAD risk factors may help reduce the number needed to screen to detect patients with positive CAC. |
X Demographics
Geographical breakdown
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Spain | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 40 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Master | 7 | 18% |
Student > Doctoral Student | 5 | 13% |
Student > Postgraduate | 4 | 10% |
Student > Bachelor | 4 | 10% |
Lecturer | 2 | 5% |
Other | 7 | 18% |
Unknown | 11 | 28% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 19 | 48% |
Biochemistry, Genetics and Molecular Biology | 2 | 5% |
Computer Science | 1 | 3% |
Neuroscience | 1 | 3% |
Chemistry | 1 | 3% |
Other | 1 | 3% |
Unknown | 15 | 38% |