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Netrin-1: Diversity in development

Overview of attention for article published in International Journal of Biochemistry & Cell Biology, March 2008
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Citations

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118 Mendeley
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3 CiteULike
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Title
Netrin-1: Diversity in development
Published in
International Journal of Biochemistry & Cell Biology, March 2008
DOI 10.1016/j.biocel.2008.03.014
Pubmed ID
Authors

DanaKai Bradford, Stacey J. Cole, Helen M. Cooper

Abstract

In 1990, the discovery of three Caenorhabditis elegans genes (unc5, unc6, unc40) involved in pioneer axon guidance and cell migration marked a significant advancement in neuroscience research [Hedgecock EM, Culotti JG, Hall DH. The unc-5, unc-6, and unc-40 genes guide circumferential migrations of pioneer axons and mesodermal cells on the epidermis in C. elegans. Neuron 1990;4:61-85]. The importance of this molecular guidance system was exemplified in 1994, when the vertebrate orthologue of Unc6, Netrin-1, was discovered to be a key guidance cue for commissural axons projecting toward the ventral midline in the rodent embryonic spinal cord [Serafini T, Kennedy TE, Galko MJ, Mirzayan C, Jessell TM, Tessier-Lavigne M. The netrins define a family of axon outgrowth-promoting proteins homologous to C. elegans UNC-6. Cell 1994;78:409-424]. Since then, Netrin-1 has been found to be a critical component of embryonic development with functions in axon guidance, cell migration, morphogenesis and angiogenesis. Netrin-1 also plays a role in the adult brain, suggesting that manipulating netrin signals may have novel therapeutic applications.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 118 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 5 4%
France 3 3%
Portugal 1 <1%
Malaysia 1 <1%
Canada 1 <1%
United Kingdom 1 <1%
Unknown 106 90%

Demographic breakdown

Readers by professional status Count As %
Researcher 26 22%
Student > Ph. D. Student 25 21%
Student > Master 11 9%
Professor > Associate Professor 10 8%
Student > Bachelor 9 8%
Other 19 16%
Unknown 18 15%
Readers by discipline Count As %
Agricultural and Biological Sciences 46 39%
Neuroscience 20 17%
Medicine and Dentistry 15 13%
Biochemistry, Genetics and Molecular Biology 9 8%
Chemistry 2 2%
Other 9 8%
Unknown 17 14%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 December 2011.
All research outputs
#8,534,976
of 25,373,627 outputs
Outputs from International Journal of Biochemistry & Cell Biology
#894
of 2,858 outputs
Outputs of similar age
#33,625
of 95,715 outputs
Outputs of similar age from International Journal of Biochemistry & Cell Biology
#9
of 20 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,858 research outputs from this source. They receive a mean Attention Score of 4.8. This one is in the 34th percentile – i.e., 34% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 95,715 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 17th percentile – i.e., 17% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 20 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.