| Title |
GBV-C: State of the Art and Future Prospects
|
|---|---|
| Published in |
Current HIV/AIDS Reports, January 2012
|
| DOI | 10.1007/s11904-011-0109-1 |
| Pubmed ID | |
| Authors |
Maria Teresa Maidana Giret, Esper Georges Kallas |
| Abstract |
The GB virus C is a common non-pathogenic virus, member of the Flaviviridae family with worldwide distribution. Favorable clinical course and reduced mortality among HIV-infected patients was demonstrated by several studies with patients co-infected with the GB virus C (GBV-C). This potential benefit of GBV-C has been demonstrated in the pre-HAART and post-HAART eras; however, this effect was not observed in all studies and the discrepancy may be due to changes during the course of HIV infection, characteristic of the cohort, and the degree of therapeutic response. The GBV-C has been found to decrease HIV replication in in vitro models, highlighting the interference of persistent GBV-C viremia. The mechanism of the beneficial effect of GBV-C appears to be mediated by changes in the cellular immune response, and elucidation of putative protective effects of GBV-C in HIV co-infection could potentially identify novel targets for anti-HIV agents. |
Mendeley readers
The data shown below were compiled from readership statistics for 41 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Netherlands | 1 | 2% |
| Brazil | 1 | 2% |
| Unknown | 39 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 9 | 22% |
| Student > Master | 8 | 20% |
| Student > Doctoral Student | 6 | 15% |
| Student > Bachelor | 4 | 10% |
| Student > Ph. D. Student | 3 | 7% |
| Other | 8 | 20% |
| Unknown | 3 | 7% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 10 | 24% |
| Medicine and Dentistry | 9 | 22% |
| Immunology and Microbiology | 5 | 12% |
| Social Sciences | 3 | 7% |
| Engineering | 2 | 5% |
| Other | 6 | 15% |
| Unknown | 6 | 15% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 August 2018.
All research outputs
#7,453,350
of 22,786,087 outputs
Outputs from Current HIV/AIDS Reports
#204
of 429 outputs
Outputs of similar age
#70,841
of 243,761 outputs
Outputs of similar age from Current HIV/AIDS Reports
#5
of 7 outputs
Altmetric has tracked 22,786,087 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 429 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.2. This one is in the 41st percentile – i.e., 41% of its peers scored the same or lower than it.
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We're also able to compare this research output to 7 others from the same source and published within six weeks on either side of this one. This one has scored higher than 2 of them.