| Title |
Medication-associated diethylene glycol mass poisoning: A review and discussion on the origin of contamination
|
|---|---|
| Published in |
Journal of Public Health Policy, July 2009
|
| DOI | 10.1057/jphp.2009.2 |
| Pubmed ID | |
| Authors |
Joshua G Schier, Carol S Rubin, Dorothy Miller, Dana Barr, Michael A McGeehin |
| Abstract |
Diethylene glycol (DEG), an extremely toxic chemical, has been implicated as the etiologic agent in at least 12 medication-associated mass poisonings over the last 70 years. Why DEG mass poisonings occur remains unclear. Most reports do not contain detailed reports of trace-back investigations into the etiology. The authors, therefore, conducted a systematic literature review on potential etiologies of these mass poisonings. The current available evidence suggests that substitution of DEG or DEG-containing compounds for pharmaceutical ingredients results from: (1) deception as to the true nature of certain ingredients by persons at some point in the pharmaceutical manufacturing process, and (2) failure to adhere to standardized quality control procedures in manufacturing pharmaceutical products intended for consumers. We discuss existing guidelines and new recommendations for prevention of these incidents. |
X Demographics
The data shown below were collected from the profiles of 17 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| India | 7 | 41% |
| United States | 1 | 6% |
| South Africa | 1 | 6% |
| Unknown | 8 | 47% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 14 | 82% |
| Science communicators (journalists, bloggers, editors) | 2 | 12% |
| Scientists | 1 | 6% |
Mendeley readers
The data shown below were compiled from readership statistics for 52 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 2% |
| Unknown | 51 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 5 | 10% |
| Other | 4 | 8% |
| Student > Postgraduate | 4 | 8% |
| Student > Ph. D. Student | 4 | 8% |
| Researcher | 4 | 8% |
| Other | 5 | 10% |
| Unknown | 26 | 50% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 9 | 17% |
| Pharmacology, Toxicology and Pharmaceutical Science | 3 | 6% |
| Agricultural and Biological Sciences | 3 | 6% |
| Engineering | 2 | 4% |
| Biochemistry, Genetics and Molecular Biology | 1 | 2% |
| Other | 4 | 8% |
| Unknown | 30 | 58% |
Attention Score in Context
This research output has an Altmetric Attention Score of 34. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 October 2022.
All research outputs
#1,200,007
of 25,770,491 outputs
Outputs from Journal of Public Health Policy
#50
of 821 outputs
Outputs of similar age
#3,383
of 123,582 outputs
Outputs of similar age from Journal of Public Health Policy
#1
of 5 outputs
Altmetric has tracked 25,770,491 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 95th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 821 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 13.8. This one has done particularly well, scoring higher than 93% of its peers.
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We're also able to compare this research output to 5 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them