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Bioprosthetic Versus Mechanical Valve Replacement for Infective Endocarditis: Focus on Recurrence Rates

Overview of attention for article published in The Annals of Thoracic Surgery, February 2018
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  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (86th percentile)
  • High Attention Score compared to outputs of the same age and source (88th percentile)

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23 X users

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Title
Bioprosthetic Versus Mechanical Valve Replacement for Infective Endocarditis: Focus on Recurrence Rates
Published in
The Annals of Thoracic Surgery, February 2018
DOI 10.1016/j.athoracsur.2017.12.046
Pubmed ID
Authors

Nana Toyoda, Shinobu Itagaki, Henry Tannous, Natalia N Egorova, Joanna Chikwe

Abstract

Consensus guidelines for prosthesis selection in infective endocarditis recommend bioprosthetic or mechanical valve replacement based on life expectancy and comorbidity. However, contemporary outcome data are limited to institution series. The outcomes of 3,447 patients identified from mandatory discharge databases in California and New York states who had either primary isolated mitral (n=1603) or aortic (n=1,844) valve replacement for active endocarditis between 1998 and 2010, were compared according to whether they received bioprosthetic (n=1,673, 48.5%) or mechanical (n=1,774, 51.5%) valves. Drug abusers were analyzed as a separate cohort. The primary outcome was endocarditis recurrence. Median follow-up time was 6.8 years (range 0-12 years). Last follow-up for survival was December 31 2015. Patients receiving bioprosthetic valves were older (60.4 ± 14.9 versus 53.4 ± 14.3 years; p<0.001), with more comorbidity. There was no significant difference in 12-year survival with bioprosthetic versus mechanical valves after mitral (adjusted HR, 1.14; 95% CI, 0.98-1.34; p=0.10) or aortic (adjusted HR, 1.10; 95% CI, 0.93-1.29; p=0.26) valve replacement. Bioprosthetic and mechanical valves were associated with similar recurrence rates at 12 years: 10.4% (95% CI, 8.0%-13.1%) versus 8.8% (95% CI, 6.9%-10.9%); adjusted Cox p=0.79 after mitral replacement, and 9.4% (95% CI, 7.5%-11.6%) versus 10.0% (95% CI, 8.0%-12.4%); adjusted Cox p=0.81 after aortic valve replacement. Bioprosthetic and mechanical valves are associated with similar survival and freedom from endocarditis recurrence. This data supports guideline recommendations that patient factors guide prosthesis choice in infective endocarditis.

X Demographics

X Demographics

The data shown below were collected from the profiles of 23 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 63 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 63 100%

Demographic breakdown

Readers by professional status Count As %
Other 7 11%
Student > Ph. D. Student 6 10%
Researcher 6 10%
Student > Bachelor 6 10%
Student > Postgraduate 4 6%
Other 15 24%
Unknown 19 30%
Readers by discipline Count As %
Medicine and Dentistry 32 51%
Nursing and Health Professions 2 3%
Engineering 2 3%
Biochemistry, Genetics and Molecular Biology 1 2%
Agricultural and Biological Sciences 1 2%
Other 4 6%
Unknown 21 33%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 13. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 March 2018.
All research outputs
#2,742,263
of 25,382,440 outputs
Outputs from The Annals of Thoracic Surgery
#528
of 8,321 outputs
Outputs of similar age
#63,325
of 455,271 outputs
Outputs of similar age from The Annals of Thoracic Surgery
#21
of 175 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. Compared to these this one has done well and is in the 89th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 8,321 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.4. This one has done particularly well, scoring higher than 93% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 455,271 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 86% of its contemporaries.
We're also able to compare this research output to 175 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 88% of its contemporaries.