| Title |
Architecture of the Trypanosoma brucei nucleus during interphase and mitosis
|
|---|---|
| Published in |
Chromosoma, March 2000
|
| DOI | 10.1007/s004120050402 |
| Pubmed ID | |
| Authors |
Emmanuel Ogbadoyi, Klaus Ersfeld, Derrick Robinson, Trevor Sherwin, Keith Gull |
| Abstract |
The structural basis of mitosis, spindle organisation and chromosome segregation, in the unicellular parasite Trypanosoma brucei is poorly understood. Here, using immunocytochemistry, fluorescent in situ hybridisation and electron microscopy, we provide a detailed analysis of mitosis in this parasite. We describe the organisation of the mitotic spindle during different stages of mitosis, the complex ultrastructure of kinetochores and the identification of a potential spindle-organising centre in the mitotic nucleus. We investigate the dynamics of chromosome segregation using telomeric and chromosome-specific probes. We also discuss the problems involved in chromosome segregation in the light of the fact that the T. brucei karyotype has 22 chromosomes in the apparent presence of only eight ultrastructurally defined kinetochores. |
Mendeley readers
The data shown below were compiled from readership statistics for 103 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| France | 2 | 2% |
| Netherlands | 1 | <1% |
| Austria | 1 | <1% |
| United Kingdom | 1 | <1% |
| United States | 1 | <1% |
| Unknown | 97 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 33 | 32% |
| Researcher | 16 | 16% |
| Student > Bachelor | 15 | 15% |
| Student > Master | 13 | 13% |
| Professor | 4 | 4% |
| Other | 8 | 8% |
| Unknown | 14 | 14% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 57 | 55% |
| Biochemistry, Genetics and Molecular Biology | 26 | 25% |
| Environmental Science | 1 | <1% |
| Pharmacology, Toxicology and Pharmaceutical Science | 1 | <1% |
| Immunology and Microbiology | 1 | <1% |
| Other | 2 | 2% |
| Unknown | 15 | 15% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 October 2022.
All research outputs
#8,534,528
of 25,371,288 outputs
Outputs from Chromosoma
#206
of 786 outputs
Outputs of similar age
#13,751
of 41,736 outputs
Outputs of similar age from Chromosoma
#2
of 2 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 786 research outputs from this source. They receive a mean Attention Score of 3.9. This one is in the 33rd percentile – i.e., 33% of its peers scored the same or lower than it.
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We're also able to compare this research output to 2 others from the same source and published within six weeks on either side of this one.