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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Chronic Helminth Infection Perturbs the Gut-Brain Axis, Promotes Neuropathology, and Alters Behavior.
|
|---|---|
| Published in |
Journal of Infectious Diseases, February 2018
|
| DOI | 10.1093/infdis/jiy092 |
| Pubmed ID | |
| Authors |
Paul R Giacomin, Ann Katrin Kraeuter, Eduardo A Albornoz, Shuting Jin, Mia Bengtsson, Richard Gordon, Trent M Woodruff, Tim Urich, Zoltán Sarnyai, Ricardo J Soares Magalhães |
| Abstract |
Helminth infections in children are associated with impaired cognitive development, however the biological mechanisms for this remain unclear. Using a murine model of gastrointestinal helminth infection, we demonstrate that early-life exposure to helminths promotes local and systemic inflammatory responses and transient changes in the gastrointestinal microbiome. Behavioural and cognitive analyses performed 9-months post-infection revealed deficits in spatial recognition memory and an anxiety-like behavioural phenotype in worm-infected mice, which was associated with neuropathology and increased microglial activation within the brain. This study demonstrates a previously unrecognised mechanism through which helminth infections may influence cognitive function, via perturbations in the gut-immune-brain axis. |
X Demographics
The data shown below were collected from the profiles of 12 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 8% |
| Netherlands | 1 | 8% |
| Turkey | 1 | 8% |
| United States | 1 | 8% |
| Australia | 1 | 8% |
| Unknown | 7 | 58% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 7 | 58% |
| Scientists | 3 | 25% |
| Science communicators (journalists, bloggers, editors) | 1 | 8% |
| Practitioners (doctors, other healthcare professionals) | 1 | 8% |
Mendeley readers
The data shown below were compiled from readership statistics for 58 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 58 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 12 | 21% |
| Student > Ph. D. Student | 7 | 12% |
| Student > Doctoral Student | 5 | 9% |
| Researcher | 5 | 9% |
| Professor > Associate Professor | 4 | 7% |
| Other | 8 | 14% |
| Unknown | 17 | 29% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 12 | 21% |
| Medicine and Dentistry | 8 | 14% |
| Agricultural and Biological Sciences | 5 | 9% |
| Neuroscience | 5 | 9% |
| Immunology and Microbiology | 3 | 5% |
| Other | 6 | 10% |
| Unknown | 19 | 33% |
Attention Score in Context
This research output has an Altmetric Attention Score of 14. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 August 2020.
All research outputs
#2,635,348
of 25,856,713 outputs
Outputs from Journal of Infectious Diseases
#1,998
of 14,943 outputs
Outputs of similar age
#62,478
of 473,971 outputs
Outputs of similar age from Journal of Infectious Diseases
#28
of 156 outputs
Altmetric has tracked 25,856,713 research outputs across all sources so far. Compared to these this one has done well and is in the 89th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 14,943 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 16.5. This one has done well, scoring higher than 86% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 473,971 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 86% of its contemporaries.
We're also able to compare this research output to 156 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 82% of its contemporaries.