Chapter title |
Control of Iron Metabolism in Bacteria
|
---|---|
Chapter number | 7 |
Book title |
Metallomics and the Cell
|
Published in |
Metal ions in life sciences, December 2012
|
DOI | 10.1007/978-94-007-5561-1_7 |
Pubmed ID | |
Book ISBNs |
978-9-40-075560-4, 978-9-40-075561-1
|
Authors |
Simon Andrews, Ian Norton, Arvindkumar S. Salunkhe, Helen Goodluck, Wafaa S. M. Aly, Hanna Mourad-Agha, Pierre Cornelis, Andrews, Simon, Norton, Ian, Salunkhe, Arvindkumar S., Goodluck, Helen, Aly, Wafaa S. M., Mourad-Agha, Hanna, Cornelis, Pierre |
Editors |
Lucia Banci |
Abstract |
Bacteria depend upon iron as a vital cofactor that enables a wide range of key metabolic activities. Bacteria must therefore ensure a balanced supply of this essential metal. To do so, they invest considerable resourse into its acquisition and employ elaborate control mechanisms to eleviate both iron-induced toxitiy as well as iron deficiency. This chapter describes the processes that bacteria engage in maintaining iron homeostasis. The focus is Escherichia coli, as this bacterium provides a well studied example. A summary of the current status of understanding of iron management at the 'omics' level is also presented. |
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Demographic breakdown
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