| Title |
Improved urethral fluorescence during low rectal surgery: a new dye and a new method
|
|---|---|
| Published in |
Techniques in Coloproctology, February 2018
|
| DOI | 10.1007/s10151-018-1757-6 |
| Pubmed ID | |
| Authors |
T. G. Barnes, D. Volpi, C. Cunningham, B. Vojnovic, R. Hompes |
| Abstract |
The aim of this study was to demonstrate highlighting of the urethra during surgery through the use of two different methods: a new near-infrared fluorophore IRDye800BK, and indocyanine green (ICG) mixed with silicone. Male cadavers from the department of anatomy at the University of Oxford were used to visualise the urethra during near-infrared fluorescence excitation. To assess IRDye800BK, a perineal incision was utilised after infiltrating the urethra directly with an IRDye800BK solution mixed with Instillagel. ICG-silicone was assessed when the urethra was purposely exposed as part of a simulated transanal total mesorectal dissection. ICG was previously mixed with ethanol and silicone and left to set in a Foley catheter. Fluorescence was visualised using an in-house manufactured fluorescence-enabled laparoscopic system. IRDye800BK demonstrated excellent penetration and visualisation of the urethra under fluorescence at an estimated tissue depth of 2 cm. An ICG-silicone catheter demonstrated excellent fluorescence without leaving any residual solution behind in the urethra after its removal. The newly described ICG-silicone method opens up the possibility of new technologies in this area of fluorescence guided surgery. IRDye800BK is a promising alternative to ICG in visualising the urethra using fluorescence imaging. Its greater depth of penetration may allow earlier detection of the urethra during surgery and prevent wrong plane surgery sooner. |
X Demographics
The data shown below were collected from the profiles of 47 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 11 | 23% |
| United Kingdom | 6 | 13% |
| Italy | 4 | 9% |
| Spain | 3 | 6% |
| South Africa | 1 | 2% |
| Argentina | 1 | 2% |
| India | 1 | 2% |
| Brazil | 1 | 2% |
| Egypt | 1 | 2% |
| Other | 1 | 2% |
| Unknown | 17 | 36% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 24 | 51% |
| Practitioners (doctors, other healthcare professionals) | 10 | 21% |
| Scientists | 9 | 19% |
| Science communicators (journalists, bloggers, editors) | 4 | 9% |
Mendeley readers
The data shown below were compiled from readership statistics for 26 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 26 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 6 | 23% |
| Student > Postgraduate | 3 | 12% |
| Other | 2 | 8% |
| Professor | 2 | 8% |
| Student > Master | 2 | 8% |
| Other | 4 | 15% |
| Unknown | 7 | 27% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 14 | 54% |
| Nursing and Health Professions | 1 | 4% |
| Business, Management and Accounting | 1 | 4% |
| Chemistry | 1 | 4% |
| Engineering | 1 | 4% |
| Other | 0 | 0% |
| Unknown | 8 | 31% |
Attention Score in Context
This research output has an Altmetric Attention Score of 25. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 May 2018.
All research outputs
#1,563,795
of 25,759,158 outputs
Outputs from Techniques in Coloproctology
#114
of 1,365 outputs
Outputs of similar age
#33,448
of 345,351 outputs
Outputs of similar age from Techniques in Coloproctology
#6
of 26 outputs
Altmetric has tracked 25,759,158 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 93rd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,365 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.5. This one has done particularly well, scoring higher than 91% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 345,351 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 90% of its contemporaries.
We're also able to compare this research output to 26 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 76% of its contemporaries.