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Agarotetrol: a source compound for low molecular weight aromatic compounds from agarwood heating

Overview of attention for article published in Journal of Natural Medicines, February 2018
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  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (70th percentile)
  • High Attention Score compared to outputs of the same age and source (87th percentile)

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Title
Agarotetrol: a source compound for low molecular weight aromatic compounds from agarwood heating
Published in
Journal of Natural Medicines, February 2018
DOI 10.1007/s11418-018-1185-y
Pubmed ID
Authors

Sakura Takamatsu, Michiho Ito

Abstract

Agarwood is known to generate a distinct fragrance upon heating and is used as both a medicine and a fragrant wood. Low molecular weight aromatic compounds (LACs) such as benzylacetone are emitted from agarwood on heating and have a sedative effect on mice. These are detected exclusively in the headspace vapor of heated agarwood and are absent in the wood itself; hence, some compounds in agarwood are thought to be converted to LACs by the process of heating. In this study, different fractions obtained from agarwood were analyzed to reveal the source compounds of LACs. Some LACs detected in the resinous agarwood were absent from the non-resinous parts and confirmed as characteristic of the resinous parts. The essential oil and hydrosol of agarwood obtained by distillation were analyzed by gas chromatography-mass spectrometry (GC-MS). Sesquiterpenes were detected in the essential oil, and sesquiterpenes and a variety of LACs were detected in the hydrosol. A hot water extract of agarwood remaining in the distillation flask after distillation was analyzed by high-performance liquid chromatography (HPLC), and agarotetrol was found to be the main compound. Purified agarotetrol was heated in a glass vial and its headspace vapor was analyzed by solid-phase microextraction GC-MS. Benzylacetone and other LACs were detected. These results indicate that agarotetrol, a chromone derivative, contributes to the fragrance of agarwood through the generation of LACs upon heating.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 21 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 21 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 4 19%
Student > Master 3 14%
Lecturer 2 10%
Student > Ph. D. Student 2 10%
Researcher 1 5%
Other 0 0%
Unknown 9 43%
Readers by discipline Count As %
Agricultural and Biological Sciences 4 19%
Biochemistry, Genetics and Molecular Biology 2 10%
Pharmacology, Toxicology and Pharmaceutical Science 2 10%
Chemistry 1 5%
Engineering 1 5%
Other 0 0%
Unknown 11 52%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 December 2022.
All research outputs
#6,127,364
of 25,059,640 outputs
Outputs from Journal of Natural Medicines
#86
of 569 outputs
Outputs of similar age
#98,258
of 336,709 outputs
Outputs of similar age from Journal of Natural Medicines
#5
of 32 outputs
Altmetric has tracked 25,059,640 research outputs across all sources so far. Compared to these this one has done well and is in the 75th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 569 research outputs from this source. They receive a mean Attention Score of 4.0. This one has done well, scoring higher than 85% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 336,709 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 70% of its contemporaries.
We're also able to compare this research output to 32 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 87% of its contemporaries.