| Title |
Diosgenin induces cell cycle arrest and apoptosis in human leukemia K562 cells with the disruption of Ca2+ homeostasis
|
|---|---|
| Published in |
Cancer Chemotherapy and Pharmacology, September 2004
|
| DOI | 10.1007/s00280-004-0849-3 |
| Pubmed ID | |
| Authors |
Ming-Jie Liu, Zhao Wang, Yong Ju, Ricky Ngok-Shun Wong, Qing-Yu Wu |
| Abstract |
Diosgenin is a steroidal sapogenin with estrogenic and antitumor properties. In order to elucidate the mechanism of its antiproliferative activity, we investigated its effects on the cell cycle and apoptosis in human chronic myelogenous leukemia K562 cells. |
Mendeley readers
The data shown below were compiled from readership statistics for 53 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Portugal | 1 | 2% |
| China | 1 | 2% |
| France | 1 | 2% |
| Unknown | 50 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 11 | 21% |
| Researcher | 8 | 15% |
| Student > Master | 6 | 11% |
| Student > Bachelor | 5 | 9% |
| Student > Doctoral Student | 3 | 6% |
| Other | 9 | 17% |
| Unknown | 11 | 21% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 10 | 19% |
| Biochemistry, Genetics and Molecular Biology | 9 | 17% |
| Chemistry | 8 | 15% |
| Pharmacology, Toxicology and Pharmaceutical Science | 4 | 8% |
| Medicine and Dentistry | 3 | 6% |
| Other | 3 | 6% |
| Unknown | 16 | 30% |
Attention Score in Context
This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 April 2024.
All research outputs
#4,972,158
of 23,815,455 outputs
Outputs from Cancer Chemotherapy and Pharmacology
#244
of 2,501 outputs
Outputs of similar age
#10,294
of 61,660 outputs
Outputs of similar age from Cancer Chemotherapy and Pharmacology
#4
of 13 outputs
Altmetric has tracked 23,815,455 research outputs across all sources so far. Compared to these this one has done well and is in the 76th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,501 research outputs from this source. They receive a mean Attention Score of 4.1. This one has done well, scoring higher than 78% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 61,660 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 72% of its contemporaries.
We're also able to compare this research output to 13 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 61% of its contemporaries.