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Neuropsychological differentiation of progressive aphasic disorders

Overview of attention for article published in Journal of Neuropsychology, February 2018
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  • Above-average Attention Score compared to outputs of the same age and source (53rd percentile)

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Title
Neuropsychological differentiation of progressive aphasic disorders
Published in
Journal of Neuropsychology, February 2018
DOI 10.1111/jnp.12149
Pubmed ID
Authors

Jennifer M. Harris, Jennifer A. Saxon, Matthew Jones, Julie S. Snowden, Jennifer C. Thompson

Abstract

The differentiation of subtypes of primary progressive aphasia (PPA) remains challenging. We aimed to identify optimum neuropsychological measures for characterizing PPA, to examine the relationship between behavioural change and subtypes of PPA and to determine whether characteristic profiles of language, working memory, and behavioural changes occur in PPA. Forty-seven patients with PPA and multi-domain Alzheimer's disease (AD) together with 19 age-matched controls underwent a large battery of working memory and language tests. We found that simple tasks of sentence ordering, narrative production, and buccofacial praxis were particularly useful in differentiating non-fluent/agrammatic variant PPA (nfvPPA) from other PPA subtypes, whereas a test of single word comprehension was useful in detecting semantic dementia (SD). No individual tests were discriminating for logopenic variant PPA (lvPPA) relative to nfvPPA. LvPPA and multidomain AD exhibited similar language profiles. A principal components analysis revealed that characteristic PPA profiles extended beyond the realms of language, in particular, the presence of apraxia in nfvPPA, behavioural changes in SD, and working memory deficits in lvPPA. These findings suggest that not all tests are equally discriminatory for PPA and highlight the importance of a test profile in differentiating PPA. These results also support the view that lvPPA is a focal form of AD and emphasize the difficulties classifying lvPPA.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 86 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 86 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 12 14%
Student > Ph. D. Student 10 12%
Student > Bachelor 9 10%
Other 7 8%
Researcher 5 6%
Other 13 15%
Unknown 30 35%
Readers by discipline Count As %
Psychology 20 23%
Neuroscience 15 17%
Medicine and Dentistry 9 10%
Nursing and Health Professions 3 3%
Linguistics 2 2%
Other 6 7%
Unknown 31 36%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 February 2018.
All research outputs
#5,763,021
of 23,023,224 outputs
Outputs from Journal of Neuropsychology
#125
of 301 outputs
Outputs of similar age
#116,385
of 439,455 outputs
Outputs of similar age from Journal of Neuropsychology
#6
of 13 outputs
Altmetric has tracked 23,023,224 research outputs across all sources so far. This one has received more attention than most of these and is in the 74th percentile.
So far Altmetric has tracked 301 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.8. This one has gotten more attention than average, scoring higher than 58% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 439,455 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 73% of its contemporaries.
We're also able to compare this research output to 13 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 53% of its contemporaries.