Title |
Receptor and nonreceptor protein tyrosine phosphatases in the nervous system
|
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Published in |
Cellular and Molecular Life Sciences, November 2003
|
DOI | 10.1007/s00018-003-3123-7 |
Pubmed ID | |
Authors |
S. Paul, P. J. Lombroso |
Abstract |
Protein tyrosine phosphatases (PTPs) have emerged as a new class of signaling molecules that play important roles in the development and function of the central nervous system. They include both tyrosine-specific and dual-specific phosphatases. Based on their cellular localization they are also classified as receptor-like or intracellular PTP. However, the intracellular mechanisms by which these PTPs regulate cellular signaling pathways are not well understood. Evidence gathered to date provides some insight into the physiological function of these PTPs in the nervous system. In this review, we outline what is currently known about the functional role of PTPs expressed in the brain. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | 1% |
Korea, Republic of | 1 | 1% |
New Zealand | 1 | 1% |
Spain | 1 | 1% |
Unknown | 84 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 18 | 20% |
Researcher | 14 | 16% |
Student > Master | 11 | 13% |
Student > Bachelor | 9 | 10% |
Professor | 5 | 6% |
Other | 14 | 16% |
Unknown | 17 | 19% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 36 | 41% |
Medicine and Dentistry | 10 | 11% |
Biochemistry, Genetics and Molecular Biology | 8 | 9% |
Neuroscience | 4 | 5% |
Chemistry | 4 | 5% |
Other | 9 | 10% |
Unknown | 17 | 19% |