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Mendeley readers
Attention Score in Context
| Title |
An Iron-Regulated Ferric Reductase Associated with the Absorption of Dietary Iron
|
|---|---|
| Published in |
Science, February 2001
|
| DOI | 10.1126/science.1057206 |
| Pubmed ID | |
| Authors |
Andrew T. McKie, Dalna Barrow, Gladys O. Latunde-Dada, Andreas Rolfs, Giamal Sager, Elida Mudaly, Melitta Mudaly, Christopher Richardson, David Barlow, Adrian Bomford, Timothy J. Peters, Kishor B. Raja, Sima Shirali, Matthias A. Hediger, Farzin Farzaneh, Robert J. Simpson |
| Abstract |
The ability of intestinal mucosa to absorb dietary ferric iron is attributed to the presence of a brush-border membrane reductase activity that displays adaptive responses to iron status. We have isolated a complementary DNA, Dcytb (for duodenal cytochrome b), which encoded a putative plasma membrane di-heme protein in mouse duodenal mucosa. Dcytb shared between 45 and 50% similarity to the cytochrome b561 family of plasma membrane reductases, was highly expressed in the brush-border membrane of duodenal enterocytes, and induced ferric reductase activity when expressed in Xenopus oocytes and cultured cells. Duodenal expression levels of Dcytb messenger RNA and protein were regulated by changes in physiological modulators of iron absorption. Thus, Dcytb provides an important element in the iron absorption pathway. |
Mendeley readers
The data shown below were compiled from readership statistics for 424 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 4 | <1% |
| Italy | 1 | <1% |
| Brazil | 1 | <1% |
| Germany | 1 | <1% |
| Canada | 1 | <1% |
| United Kingdom | 1 | <1% |
| Greece | 1 | <1% |
| Poland | 1 | <1% |
| Unknown | 413 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 72 | 17% |
| Student > Master | 58 | 14% |
| Researcher | 53 | 13% |
| Student > Bachelor | 51 | 12% |
| Student > Doctoral Student | 33 | 8% |
| Other | 76 | 18% |
| Unknown | 81 | 19% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 104 | 25% |
| Biochemistry, Genetics and Molecular Biology | 88 | 21% |
| Medicine and Dentistry | 59 | 14% |
| Chemistry | 20 | 5% |
| Immunology and Microbiology | 15 | 4% |
| Other | 50 | 12% |
| Unknown | 88 | 21% |
Attention Score in Context
This research output has an Altmetric Attention Score of 9. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 June 2023.
All research outputs
#3,799,086
of 25,377,790 outputs
Outputs from Science
#37,367
of 82,914 outputs
Outputs of similar age
#6,836
of 113,964 outputs
Outputs of similar age from Science
#92
of 256 outputs
Altmetric has tracked 25,377,790 research outputs across all sources so far. Compared to these this one has done well and is in the 83rd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 82,914 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 65.7. This one has gotten more attention than average, scoring higher than 52% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 113,964 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 91% of its contemporaries.
We're also able to compare this research output to 256 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 60% of its contemporaries.