| Title |
Thromboxanes: Synthase and receptors
|
|---|---|
| Published in |
Journal of Biomedical Science, May 1998
|
| DOI | 10.1007/bf02253465 |
| Pubmed ID | |
| Authors |
Rong-Fong Shen, Hsin-Hsiung Tai |
| Abstract |
Thromboxane A2 is a biologically potent arachidonate metabolite through the cyclooxygenase pathway. It induces platelet aggregation and smooth muscle contraction and may promote mitogenesis and apoptosis of other cells. Its roles in physiological and pathological conditions have been widely documented. The enzyme that catalyzes its synthesis, thromboxane A2 synthase, and the receptors that mediate its actions, thromboxane A2 receptors, are the two key components critical for the functioning of this potent autacoid. Recent molecular biological studies have revealed the structure-function relationship and gene organizations of these proteins as well as genetic and epigenetic factors modulating their gene expression. Future investigation should shed light on detailed molecular signaling events specifying thromboxane A2 actions, and the genetic underpinning of the enzyme and the receptors in health and disease. |
Mendeley readers
The data shown below were compiled from readership statistics for 8 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 8 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Professor > Associate Professor | 3 | 38% |
| Student > Master | 2 | 25% |
| Student > Bachelor | 1 | 13% |
| Student > Ph. D. Student | 1 | 13% |
| Unknown | 1 | 13% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 3 | 38% |
| Agricultural and Biological Sciences | 1 | 13% |
| Chemistry | 1 | 13% |
| Sports and Recreations | 1 | 13% |
| Unknown | 2 | 25% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 December 2012.
All research outputs
#7,453,350
of 22,786,087 outputs
Outputs from Journal of Biomedical Science
#297
of 986 outputs
Outputs of similar age
#10,392
of 34,218 outputs
Outputs of similar age from Journal of Biomedical Science
#1
of 2 outputs
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So far Altmetric has tracked 986 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.4. This one is in the 45th percentile – i.e., 45% of its peers scored the same or lower than it.
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